SCHEMBL20089290

SCHEMBL20089290

CC(=O)c1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1[S+]([O-])C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRP O00591 20/20 0.53
GABRD O14764 20/20 0.53
GABRA1 P14867 20/20 0.53
GABRB1 P18505 20/20 0.53
GABRG2 P18507 20/20 0.53
GABRB3 P28472 20/20 0.53
GABRA5 P31644 20/20 0.53
GABRA3 P34903 20/20 0.53
GABRA2 P47869 20/20 0.53
GABRB2 P47870 20/20 0.53
GABRA4 P48169 20/20 0.53
GABRE P78334 20/20 0.53
GABRA6 Q16445 20/20 0.53
GABRG1 Q8N1C3 20/20 0.53
GABRG3 Q99928 20/20 0.53
GABRQ Q9UN88 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25897 0.90 GABRP (0.51) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18393472 0.90 GABRA2 (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7779071 0.90 GABRP (0.51) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL4751430 0.89 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL5203598 0.87 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL33214 0.86 GABRP (0.52) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7496634 0.86 GABRP (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7247054 0.86 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7715369 0.86 GABRP (0.62) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7023353 0.84 GABRP (0.50) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180110222-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2018-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180110222-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CHRM3, CHRM5, CHRM2 GABRP 500/4885GABRD 631/4885GABRA1 387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.