Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 2/20 | 0.41 |
| ▸ | GJB2 | P29033 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | GJA1 | P17302 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | CDC25B | P30305 | 4/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18412650 | 1.00 | LGALS3 (0.41) | LGALS3GJB2SLC6A2SSTR4NT5E | |
| SCHEMBL20243568 | 1.00 | LGALS3 (0.41) | LGALS3GJB2SLC6A2SSTR4NT5E | |
| SCHEMBL18412635 | 0.92 | LGALS3 (0.38) | LGALS3GJB2SSTR4NT5EGJA1 | |
| SCHEMBL24059833 | 0.87 | NT5E (0.47) | LGALS3GJB2SSTR4NT5EPTPN1 | |
| SCHEMBL22013736 | 0.87 | NT5E (0.47) | LGALS3GJB2SSTR4NT5EPTPN1 | |
| SCHEMBL18394464 | 0.87 | NT5E (0.47) | LGALS3GJB2SSTR4NT5EPTPN1 | |
| SCHEMBL18394265 | 0.83 | GJB2 (0.35) | LGALS3GJB2SSTR4NT5EPTPN1 | |
| SCHEMBL22013739 | 0.83 | GJB2 (0.35) | LGALS3GJB2SSTR4NT5EPTPN1 | |
| SCHEMBL22991832 | 0.83 | GJB2 (0.35) | LGALS3GJB2SSTR4NT5EPTPN1 | |
| SCHEMBL20648775 | 0.82 | LGALS3 (0.48) | LGALS3GJB2SLC6A2SSTR4NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185838-A1 | CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN | UNIV BASEL (CH) | 2022-06-16 | — | — | US | disclosed |
| US-11220523-B2 | Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein | UNIVERSITÄT BASEL (CH) | 2022-01-11 | — | — | US | disclosed |
| EP-3915999-A1 | CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN | Universität Basel (CH) | 2021-12-01 | — | — | EP | disclosed |
| US-20210061838-A1 | CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN | UNIVERSITAET BASEL (CH) | 2021-03-04 | — | — | US | disclosed |
| EP-3116887-B1 | CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN | UNIV BASEL (CH) | 2021-02-17 | — | — | EP | disclosed |
| US-10662212-B2 | Carbohydrate ligands that bind to IGM antibodies against myelin-associated glycoprotein | UNIVERSITAT BASEL (CH) | 2020-05-26 | — | — | US | disclosed |
| US-20180327438-A1 | CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN | UNIVERSITAET BASEL (CH) | 2018-11-15 | — | — | US | disclosed |
| US-9994605-B2 | Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein | UNIVERSITAET BASEL (CH) | 2018-06-12 | — | — | US | disclosed |
| US-20170022239-A1 | CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN | UNIVERSITAET BASEL (CH) | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11220523-B2 | Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein | MAG, PMP22, SIGLEC7 | LGALS3 84/4885GJB2 991/4885SLC6A2 3983/4885 |
| US-20220185838-A1 | CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN | MAG, PMP22, SIGLEC7 | LGALS3 84/4885GJB2 991/4885SLC6A2 3983/4885 |
| US-10662212-B2 | Carbohydrate ligands that bind to IGM antibodies against myelin-associated glycoprotein | MAG, PMP22, SIGLEC7 | LGALS3 87/4885GJB2 875/4885SLC6A2 3953/4885 |
| US-20210061838-A1 | CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN | MAG, PMP22, SIGLEC7 | LGALS3 84/4885GJB2 991/4885SLC6A2 3983/4885 |
| US-20170022239-A1 | CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN | MAG, PMP22, SIGLEC7 | LGALS3 84/4885GJB2 991/4885SLC6A2 3983/4885 |
| US-20180327438-A1 | CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN | MAG, PMP22, SIGLEC7 | LGALS3 87/4885GJB2 875/4885SLC6A2 3953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.