SCHEMBL22013739

SCHEMBL22013739

CC1(C)OC2C(OCc3ccccc3)[C@H](Oc3ccc(CCN=[N+]=[N-])cc3)OC(COCc3ccccc3)[C@@H]2O1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GJB2 P29033 2/20 0.35
▸ NT5E P21589 1/20 0.35
▸ SSTR4 P31391 2/20 0.34
▸ SSTR1 P30872 1/20 0.34
▸ SSTR2 P30874 1/20 0.34
▸ SSTR3 P32745 1/20 0.34
▸ SSTR5 P35346 1/20 0.34
▸ PTPN1 P18031 6/20 0.34
▸ CDC25B P30305 4/20 0.34
▸ HTR1A P08908 1/20 0.33
▸ LGALS3 P17931 2/20 0.33
▸ PTPN2 P17706 4/20 0.32
▸ PTPN6 P29350 2/20 0.31
▸ PTPN11 Q06124 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18394265 1.00 GJB2 (0.35) GJB2NT5ESSTR4SSTR1SSTR2
SCHEMBL22991832 1.00 GJB2 (0.35) GJB2NT5ESSTR4SSTR1SSTR2
SCHEMBL18412648 0.88 HTR1A (0.35) GJB2NT5ESSTR4SSTR1SSTR2
SCHEMBL20243570 0.88 HTR1A (0.35) GJB2NT5ESSTR4SSTR1SSTR2
SCHEMBL11886555 0.84 SSTR1 (0.40) GJB2NT5ESSTR4SSTR1SSTR2
SCHEMBL22842844 0.84 SSTR1 (0.39) GJB2NT5ESSTR4SSTR1SSTR2
SCHEMBL25964180 0.84 SSTR1 (0.39) GJB2NT5ESSTR4SSTR1SSTR2
SCHEMBL20243568 0.83 LGALS3 (0.41) GJB2NT5ESSTR4SSTR5PTPN1
SCHEMBL18412650 0.83 LGALS3 (0.41) GJB2NT5ESSTR4SSTR5PTPN1
SCHEMBL18394344 0.83 LGALS3 (0.41) GJB2NT5ESSTR4SSTR5PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220185838-A1 CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN UNIV BASEL (CH) 2022-06-16 — — US disclosed
US-11220523-B2 Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein UNIVERSITÄT BASEL (CH) 2022-01-11 — — US disclosed
EP-3915999-A1 CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN Universität Basel (CH) 2021-12-01 — — EP disclosed
US-10662212-B2 Carbohydrate ligands that bind to IGM antibodies against myelin-associated glycoprotein UNIVERSITAT BASEL (CH) 2020-05-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11220523-B2 Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein MAG, PMP22, SIGLEC7 GJB2 991/4885NT5E 1595/4885SSTR4 3663/4885
US-20220185838-A1 CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN MAG, PMP22, SIGLEC7 GJB2 991/4885NT5E 1595/4885SSTR4 3663/4885
US-10662212-B2 Carbohydrate ligands that bind to IGM antibodies against myelin-associated glycoprotein MAG, PMP22, SIGLEC7 GJB2 875/4885NT5E 1622/4885SSTR4 3680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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