Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | F3 | P13726 | 3/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aphidicolin SCHEMBL14667945 | 1.00 | POLA1 (1.00) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Aphidicolin SCHEMBL16610406 | 1.00 | POLA1 (1.00) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Aphidicolin SCHEMBL8763668 | 1.00 | POLA1 (1.00) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| SCHEMBL14552897 | 0.84 | LMNA (0.73) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29351943 | 0.82 | CYP2C19 (0.98) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Aphidicolin SCHEMBL2332951 | 0.77 | POLA1 (0.59) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| SCHEMBL15747 | 0.76 | CYP2C19 (0.70) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Temoporfin SCHEMBL8660214 | 0.73 | POLA1 (0.54) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| SCHEMBL29483361 | 0.72 | LMNA (0.56) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Stemodin SCHEMBL15978379 | 0.64 | LMNA (0.47) | POLA1LMNAHTTRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5380 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3841097-B1 | 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER | BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) | 2026-05-20 | — | — | EP | claimed |
| US-12605407-B2 | Methods to induce terminal differentiation in stem cells by interfering with DNA replication, methods of inducing pancreatic differentiation, and differentiated cells obtained thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2026-04-21 | — | — | US | claimed |
| EP-4346928-B1 | BIODEGRADABLE TISSUE SCAFFOLD WITH SECONDARY MATRIX TO HOST WEAKLY ADHERENT CELLS | US HEALTH (US) | 2026-01-14 | — | — | EP | claimed |
| US-20250340836-A1 | METHODS FOR PRODUCTION OF IPSCS | NEW YORK STEM CELL FOUND INC (US) | 2025-11-06 | — | — | US | claimed |
| US-20250325717-A1 | ANTI-NUCLEOPHOSMIN 1 ANTIBODY AND ANTIBODY CONJUGATE COMBINATION THERAPIES | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-10-23 | — | — | US | claimed |
| US-20250320515-A1 | GREENHOUSE-BASED PRODUCTION OF FUNGAL-DERIVED MEDICINAL COMPOUNDS | UNIV NORTH TEXAS (US) | 2025-10-16 | — | — | US | claimed |
| US-20250313647-A1 | MUTANT AND MISLOCALIZED CELL SURFACE NUCLEOPHOSMIN 1 AS A DIAGNOSTIC AND THERAPEUTIC TARGET OF HUMAN DISEASE | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-10-09 | — | — | US | claimed |
| US-20250302977-A1 | ANTIBODY-DRUG CONJUGATES COMPRISING HUMANIZED ANTIBODIES TARGETING UROKINASE TYPE PLASMINOGEN ACTIVATOR RECEPTOR ASSOCIATED PROTEIN (UPARAP) | RIGSHOSPITALET (DK) | 2025-10-02 | — | — | US | claimed |
| WO-2025202361-A1 | ANTI-GPC1 ANTIBODIES AND USES THEREOF | ADCENDO APS (DK) | 2025-10-02 | — | — | WO | claimed |
| US-12428677-B2 | Thermally responsive conjugates for DNA polymerase inhibition | Tozaro Limited (GB) | 2025-09-30 | — | — | US | claimed |
| WO-1996006863-A1 | AGENTS FOR INDUCING APOPTOSIS AND APPLICATIONS OF SAID AGENTS IN THERAPY | UNIVERSITY OF DUNDEE (GB) | 1996-03-07 | — | — | WO | claimed |
| EP-0658117-A1 | TREATMENT OF TUMORS WITH NEUROTROPHIC FACTORS AND CELL PROLIFERATION INHIBITORS | THE WORCESTER FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1995-06-21 | — | — | EP | claimed |
| US-5387520-A | Contacting neuroblastoma cells with nerve growth factor and one of aphidicolin, hydroxyurea or thymidine for one to fifteen days | WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY (US) | 1995-02-07 | — | — | US | claimed |
| EP-0315782-B1 | Method for the production of proteins | THOMAE GMBH DR K (DE) | 1994-09-28 | — | — | EP | claimed |
| WO-1994005315-A1 | TREATMENT OF TUMORS WITH NEUROTROPHIC FACTORS AND CELL PROLIFERATION INHIBITORS | WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY (US) | 1994-03-17 | — | — | WO | claimed |
| US-5202244-A | PROCESS FOR PRODUCING APHIDICOLIN USING THE MICRORGANISM VERTICILLIUM SP | NIPPON MEKTRON LIMITED (JP) | 1993-04-13 | — | — | US | claimed |
| US-5008252-A | Using viricides 5'ethynyl-thymidine | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1991-04-16 | — | — | US | claimed |
| EP-0315782-A2 | Method for the production of proteins | Dr. Karl Thomae GmbH (DE) | 1989-05-17 | — | — | EP | claimed |
| EP-0112603-B1 | APHIDICOLANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-04 | — | — | EP | claimed |
| EP-0112603-A1 | Aphidicolane derivatives, their preparation and pharmaceutical compositions comprising them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-07-04 | — | — | EP | claimed |