Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | F3 | P13726 | 3/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aphidicolin SCHEMBL14667945 | 1.00 | POLA1 (1.00) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Aphidicolin SCHEMBL183956 | 1.00 | POLA1 (1.00) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Aphidicolin SCHEMBL8763668 | 1.00 | POLA1 (1.00) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| SCHEMBL14552897 | 0.84 | LMNA (0.73) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29351943 | 0.82 | CYP2C19 (0.98) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Aphidicolin SCHEMBL2332951 | 0.77 | POLA1 (0.59) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| SCHEMBL15747 | 0.76 | CYP2C19 (0.70) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Temoporfin SCHEMBL8660214 | 0.73 | POLA1 (0.54) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| SCHEMBL29483361 | 0.72 | LMNA (0.56) | POLA1LMNAHTTRECQLSMN1; SMN2 | |
| Stemodin SCHEMBL15978379 | 0.64 | LMNA (0.47) | POLA1LMNAHTTRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150093371-A1 | ANTIVIRAL COMPOSITIONS AND METHODS OF THEIR USE | Humanitas Technology, LLC (US) | 2015-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150093371-A1 | ANTIVIRAL COMPOSITIONS AND METHODS OF THEIR USE | DDX5, MAVS, EIF2AK2 | POLA1 1649/4885LMNA 3080/4885HTT 3620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.