Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aphidicolin SCHEMBL20770430 | 0.78 | POLA1 (0.74) | POLA1LMNASMN1; SMN2HTTRECQL | |
| Aphidicolin SCHEMBL8763668 | 0.77 | POLA1 (1.00) | POLA1LMNASMN1; SMN2HTTRECQL | |
| Aphidicolin SCHEMBL183956 | 0.77 | POLA1 (1.00) | POLA1LMNASMN1; SMN2HTTRECQL | |
| Aphidicolin SCHEMBL16610406 | 0.77 | POLA1 (1.00) | POLA1LMNASMN1; SMN2HTTRECQL | |
| Aphidicolin SCHEMBL14667945 | 0.77 | POLA1 (1.00) | POLA1LMNASMN1; SMN2HTTRECQL | |
| Aphidicolin SCHEMBL20771749 | 0.72 | LMNA (0.61) | POLA1LMNASMN1; SMN2HTTRECQL | |
| Aphidicolin SCHEMBL20771139 | 0.71 | POLA1 (0.71) | POLA1LMNASMN1; SMN2HTTRECQL | |
| Hydrochloric Acid SCHEMBL29351943 | 0.68 | CYP2C19 (0.98) | POLA1LMNASMN1; SMN2HTTRECQL | |
| Dacarbazine SCHEMBL5560 | 0.68 | PAX8 (0.59) | LMNASMN1; SMN2CYP2C19TSHRPAX8 | |
| Dacarbazine SCHEMBL6372 | 0.68 | PAX8 (0.59) | LMNASMN1; SMN2CYP2C19TSHRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356093-A1 | Carbazole compounds and therapeutic uses of the compounds | INCURON, LLC (RU) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010042445-A1 | CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS | CLEVELAND BIOLABS, INC. (US) | 2010-04-15 | — | — | WO | disclosed |