Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17143141 | 0.95 | HTR3A (0.48) | HTR3AKCNH2ADRA2AADRA2BHTR4 | |
| SCHEMBL17142947 | 0.93 | KMT2A (0.46) | HTR3AKCNH2ADRA2AADRA2BHTR4 | |
| SCHEMBL17142411 | 0.93 | NAMPT (0.47) | HTR3AKCNH2ADRA2AADRA2BHTR4 | |
| SCHEMBL17148153 | 0.93 | EPHX2 (0.49) | EPHX2NAMPTKMT2ALMNAPOLB | |
| SCHEMBL18394576 | 0.90 | HTR1F (0.48) | NAMPTKMT2ALMNAHTR1FPOLB | |
| SCHEMBL17142435 | 0.90 | EPHX2 (0.48) | EPHX2KMT2ALMNAHTR1FPOLB | |
| SCHEMBL17142872 | 0.89 | EPHX2 (0.47) | EPHX2NAMPTKMT2ALMNAPOLB | |
| SCHEMBL17148308 | 0.88 | KMT2A (0.48) | EPHX2KMT2ALMNAHTR1FPOLB | |
| SCHEMBL18394359 | 0.88 | HTR1F (0.44) | KMT2ALMNAHTR1FPOLBKDM4E | |
| SCHEMBL19840635 | 0.86 | EPHX2 (0.45) | KCNH2ADRA2AADRA2BHTR4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884063-B2 | Amido-substituted azole compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-02-06 | — | — | US | disclosed |
| US-9884063-B2 | Amido-substituted azole compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-02-06 | — | — | US | disclosed |
| US-20170020886-A1 | AMIDO-SUBSTITUTED AZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170020886-A1 | AMIDO-SUBSTITUTED AZOLE COMPOUNDS | TNK1, TNNI3K, TNKS | HTR3A 4365/4885KCNH2 1141/4885ADRA2A 3261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.