Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.36 |
| ▸ | HTR3B | O95264 | 3/20 | 0.36 |
| ▸ | HTR3A | P46098 | 3/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620550 | 0.81 | TDP1 (0.47) | ALDH1A1ADORA2ACYP2C19HSD17B10MAPT | |
| SCHEMBL17620584 | 0.80 | ADORA2A (0.46) | ALDH1A1ADORA2AHSD17B10MAPTMEN1 | |
| SCHEMBL17620538 | 0.80 | CYP11B2 (0.39) | ALDH1A1CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL17634370 | 0.80 | MAPT (0.43) | ALDH1A1CYP1A2CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL17620555 | 0.79 | SMN1; SMN2 (0.46) | ALDH1A1ADORA2AHSD17B10MAPTMEN1 | |
| SCHEMBL17620593 | 0.78 | ADORA2A (0.50) | ALDH1A1ADORA2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL17620537 | 0.78 | LMNA (0.42) | ALDH1A1ADORA2ACYP1A2CYP3A4MAPT | |
| SCHEMBL18396448 | 0.77 | PTGS1 (0.37) | ACHEALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL17634375 | 0.76 | L3MBTL1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2ALOX15 | |
| SCHEMBL17620539 | 0.76 | L3MBTL1 (0.52) | ALDH1A1HSD17B10MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017014601-A1 | INDOLIZINO [3,2-C] QUINOLINE-BASED FLUORESCENT PROBE | 서울대학교 산학협력단 | 2017-01-26 | — | — | WO | disclosed |