Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7908264 | 0.89 | ALDH1A1 (0.35) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL13498680 | 0.87 | ALDH1A1 (0.46) | ALDH1A1HPGDMEN1KMT2ACYP17A1 | |
| SCHEMBL1509167 | 0.83 | GAA (0.41) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8723108 | 0.83 | ALDH1A1 (0.35) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL15600318 | 0.80 | CA1 (0.50) | GAAALDH1A1HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1509184 | 0.79 | ALDH1A1 (0.39) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL130859 | 0.79 | NAMPT (0.47) | GAAMEN1KMT2ANAMPTHDAC1 | |
| SCHEMBL13746395 | 0.79 | RAB9A (0.48) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL15355087 | 0.77 | ALDH1A1 (0.39) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10168511 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HPGDMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2478049-B1 | A POLYMER SUPPORT | UNIV CAPE TOWN (ZA) | 2015-02-25 | — | — | EP | claimed |
| US-8420802-B2 | Polymer support | UNIVERSITY OF CAPE TOWN (ZA) | 2013-04-16 | — | — | US | claimed |
| CN-102639627-A | A polymer support | UNIV CAPE TOWN | 2012-08-15 | — | — | CN | claimed |
| EP-2478049-A1 | A POLYMER SUPPORT | University of Cape Town (ZA) | 2012-07-25 | — | — | EP | claimed |
| US-20120178916-A1 | Polymer Support | UNIVERSITY OF CAPE TOWN (ZA) | 2012-07-12 | — | — | US | claimed |
| WO-2011083360-A1 | A POLYMER SUPPORT | UNIVERSITY OF CAPE TOWN (ZA) | 2011-07-14 | — | — | WO | claimed |
| JP-3027356-A | — | — | None | — | — | JP | disclosed |
| EP-4089074-A1 | PSMA-BINDING AGENTS AND USES THEREOF | The Johns Hopkins University (US) | 2022-11-16 | — | — | EP | disclosed |
| EP-3222615-B1 | PSMA-BINDING AGENTS AND USES THEREOF | UNIV JOHNS HOPKINS (US) | 2022-05-04 | — | — | EP | disclosed |
| US-20220088229-A1 | PSMA-BINDING AGENTS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSTY | 2022-03-24 | — | — | US | disclosed |
| US-20220023437-A1 | HUMANIZED ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE | GENENTECH, INC. (US) | 2022-01-27 | — | — | US | disclosed |
| US-RE48558-E1 | Anti-CD79B antibodies and immunoconjugates and methods of use | GENENTECH, INC. (US) | 2021-05-18 | — | — | US | disclosed |
| US-10981987-B2 | Humanized anti-CD79b antibodies and immunoconjugates and methods of use | GENENTECH, INC. (US) | 2021-04-20 | — | — | US | disclosed |
| US-6217845-B1 | IMAGING; THERAPY | ANORMED, INC. (CA) | 2001-04-17 | — | — | US | disclosed |
| US-5753520-A | BIOCHEMICAL CONJUGATED WITH A HYDRAZINE OR A HYDRAZONE COMPOUND AS DRUG DELIVERY; HIGH BIOLOGICAL SPECIFICITY; MEDICINE FOR IMAGING, THERAPY, RADIOACTIVE TAGGING | JOHNSON MATTHEY INC. (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0384769-B1 | Protein labelling | JOHNSON MATTHEY PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5420285-A | Imaging for medicine | JOHNSON MATTHEY, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| US-5206370-A | Certain pyridyl hydrazines and hydrazides useful for protein labeling | JOHNSON MATTHEY, INC. (US) | 1993-04-27 | — | — | US | disclosed |
| JP-H0327356-A | LABELING OF PROTEIN | JOHNSON MATTHEY INC | 1991-02-05 | — | — | JP | disclosed |
| EP-0384769-A2 | Protein labelling | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1990-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981987-B2 | Humanized anti-CD79b antibodies and immunoconjugates and methods of use | CD99, CD79B, CD47 | GAA 1224/4885ALDH1A1 2739/4885HPGD 4019/4885 |
| US-20220023437-A1 | HUMANIZED ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE | CD99, CD79B, CD47 | GAA 1224/4885ALDH1A1 2739/4885HPGD 4019/4885 |
| US-20220088229-A1 | PSMA-BINDING AGENTS AND USES THEREOF | KLK3, FOLH1, DNPEP | GAA 197/4885ALDH1A1 1693/4885HPGD 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.