Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723108 | 0.94 | ALDH1A1 (0.35) | ALDH1A1GAAHPGDMAPTLMNA | |
| SCHEMBL1839770 | 0.89 | GAA (0.41) | ALDH1A1GAAHPGDNPC1RAB9A | |
| SCHEMBL13498680 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HPGDMEN1KMT2ACYP17A1 | |
| SCHEMBL7907263 | 0.79 | MAPT (0.46) | ALDH1A1GAAHPGDMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL1509184 | 0.74 | ALDH1A1 (0.39) | ALDH1A1GAAHPGDMAPTLMNA | |
| SCHEMBL130859 | 0.74 | NAMPT (0.47) | GAAMAPTLMNANPSR1MEN1 | |
| SCHEMBL8728287 | 0.74 | MAPT (0.41) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL1509167 | 0.73 | GAA (0.41) | GAANPC1RAB9AMEN1KMT2A | |
| SCHEMBL10168511 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTLMNANPC1 | |
| SCHEMBL7990866 | 0.71 | CYP17A1 (0.38) | HPGDNFKB1NFKB2RELACYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6217845-B1 | IMAGING; THERAPY | ANORMED, INC. (CA) | 2001-04-17 | — | — | US | disclosed |
| EP-0384769-B1 | Protein labelling | JOHNSON MATTHEY PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5206370-A | Certain pyridyl hydrazines and hydrazides useful for protein labeling | JOHNSON MATTHEY, INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0384769-A2 | Protein labelling | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1990-08-29 | — | — | EP | disclosed |