Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18397705 | 1.00 | EIF2AK2 (0.45) | EIF2AK2CSNK2A2CSNK2BCSNK2A1CA1 | |
| SCHEMBL8187374 | 0.89 | EIF2AK2 (0.44) | EIF2AK2CSNK2A2CSNK2BCSNK2A1CA1 | |
| SCHEMBL8187372 | 0.89 | EIF2AK2 (0.44) | EIF2AK2CSNK2A2CSNK2BCSNK2A1CA1 | |
| SCHEMBL6010545 | 0.81 | MIF (0.56) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL11360218 | 0.80 | NOS2 (0.48) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL11360222 | 0.80 | NOS2 (0.48) | CA1CA2NFKB1CA4MIF | |
| SCHEMBL5862648 | 0.79 | EIF2AK2 (0.55) | EIF2AK2CSNK2A2CSNK2BCSNK2A1CA1 | |
| SCHEMBL5862650 | 0.79 | EIF2AK2 (0.55) | EIF2AK2CSNK2A2CSNK2BCSNK2A1CA1 | |
| SCHEMBL448705 | 0.77 | CA1 (0.56) | CA1CA2NFKB1CA4SLC22A12 | |
| SCHEMBL3864311 | 0.77 | ERN1 (0.58) | EIF2AK2CSNK2A2CSNK2BCSNK2A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215740-A1 | PARA-SUBSTITUTED INDANYL AND TETRALINYL DERIVATIVES | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| EP-3325439-A1 | PARA-SUBSTITUTED INDANYL AND TETRALINYL DERIVATIVES | BASF SE (DE) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017012938-A1 | PARA-SUBSTITUTED INDANYL AND TETRALINYL DERIVATIVES | BASF SE (DE) | 2017-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215740-A1 | PARA-SUBSTITUTED INDANYL AND TETRALINYL DERIVATIVES | CYP4F2, INTS6, CYP11B2 | EIF2AK2 1401/4885CSNK2A2 465/4885CSNK2B 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.