Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162969 | 0.88 | MIF (0.58) | MIFCA1CA2CA4TYR | |
| SCHEMBL31609339 | 0.88 | MIF (0.58) | MIFCA1CA2CA4TYR | |
| SCHEMBL162970 | 0.88 | MIF (0.58) | MIFCA1CA2CA4TYR | |
| SCHEMBL11360218 | 0.81 | NOS2 (0.48) | MIFCA1CA2CA4ESR1 | |
| SCHEMBL11360222 | 0.81 | NOS2 (0.48) | MIFCA1CA2CA4ESR1 | |
| SCHEMBL18397706 | 0.81 | EIF2AK2 (0.45) | MIFCA1CA2CA4NFKB1 | |
| SCHEMBL18397705 | 0.81 | EIF2AK2 (0.45) | MIFCA1CA2CA4NFKB1 | |
| SCHEMBL448705 | 0.79 | CA1 (0.56) | CA1CA2CA4HCAR2NFKB1 | |
| SCHEMBL448706 | 0.79 | CA1 (0.56) | CA1CA2CA4HCAR2NFKB1 | |
| SCHEMBL852543 | 0.79 | CA1 (0.56) | CA1CA2CA4HCAR2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711833-A2 | PREPARATION OF BIOLOGICALLY DERIVED FLUIDS FOR BIOMARKER DETERMINATION BY MASS SPECTROMETRY | Applera Corporation (US) | 2006-10-18 | — | — | EP | disclosed |
| US-20050196789-A1 | Preparation of biologically derived fluids for biomarker determination by mass spectrometry | APPLERA CORPORATION (US) | 2005-09-08 | — | — | US | disclosed |
| WO-2005078440-A2 | PREPARATION OF BIOLOGICALLY DERIVED FLUIDS FOR BIOMARKER DETERMINATION BY MASS SPECTROMETRY | APPLERA CORPORATION (US) | 2005-08-25 | — | — | WO | disclosed |