Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18398918 | 0.86 | SLC6A3 (0.42) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL18398929 | 0.86 | — | — | |
| SCHEMBL18399247 | 0.84 | DRD2 (0.36) | — | |
| SCHEMBL18115238 | 0.81 | SLC6A3 (0.46) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL1442814 | 0.80 | SLC6A3 (0.45) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL18398975 | 0.79 | SLC6A3 (0.44) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL18398996 | 0.78 | SLC6A3 (0.42) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL28834106 | 0.76 | SLC6A3 (0.44) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL31224477 | 0.73 | SLC6A3 (0.59) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL18399312 | 0.73 | REN (0.40) | SLC6A3KCNH2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325449-A1 | COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017012576-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-01-26 | — | — | WO | disclosed |