Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18399078 | 0.81 | SLC6A3 (0.46) | — | |
| SCHEMBL18398981 | 0.77 | DRD2 (0.49) | DRD2DRD3HTR1A | |
| SCHEMBL18399180 | 0.76 | TAAR1 (0.39) | DRD2DRD3 | |
| SCHEMBL27700096 | 0.75 | PRKACA (0.42) | DRD2DRD3 | |
| SCHEMBL20038176 | 0.73 | — | — | |
| SCHEMBL2325497 | 0.73 | — | — | |
| SCHEMBL27680906 | 0.73 | PRKACA (0.43) | DRD2DRD3HTR1A | |
| SCHEMBL18399247 | 0.73 | DRD2 (0.36) | DRD2DRD3 | |
| SCHEMBL28900236 | 0.71 | DRD2 (0.46) | DRD2DRD3HTR1A | |
| SCHEMBL18398975 | 0.70 | SLC6A3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3325449-A1 | COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017012576-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-01-26 | — | — | WO | disclosed |