Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CLK3 | P49761 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1841391 | 0.87 | CCR1 (0.39) | KDM4EALDH1A1MAPTCCR1MEN1 | |
| SCHEMBL1842532 | 0.87 | KDM4E (0.36) | KDM4EALDH1A1MAPTCCR1MEN1 | |
| SCHEMBL1840039 | 0.85 | KDM4E (0.34) | KDM4EALDH1A1MAPTCCR1MEN1 | |
| SCHEMBL1842443 | 0.84 | MAPT (0.36) | KDM4EALDH1A1MAPTCCR1MEN1 | |
| SCHEMBL1839734 | 0.82 | CCR1 (0.36) | KDM4EALDH1A1MAPTCCR1MEN1 | |
| SCHEMBL1842383 | 0.81 | CCR1 (0.36) | KDM4EALDH1A1MAPTCCR1MEN1 | |
| SCHEMBL1841550 | 0.81 | CCR1 (0.35) | KDM4EALDH1A1MAPTCCR1MEN1 | |
| SCHEMBL1845558 | 0.80 | CCR1 (0.40) | KDM4EALDH1A1MAPTCCR1FGFR4 | |
| SCHEMBL1839932 | 0.80 | BRPF1 (0.42) | KMT2ARAB9AMAPK1BRPF1WNT1 | |
| SCHEMBL2010061 | 0.80 | BRPF1 (0.42) | KMT2ARAB9AMAPK1BRPF1WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091944-B1 | SUBSTITUTED BICYCLOCARBOXYAMIDE COMPOUNDS | PFIZER (US) | 2011-05-18 | — | — | EP | claimed |