Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842383 | 0.92 | CCR1 (0.36) | CCR1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL1842443 | 0.91 | MAPT (0.36) | CCR1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL1841550 | 0.91 | CCR1 (0.35) | CCR1KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL1839936 | 0.82 | KDM4E (0.35) | CCR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL1841391 | 0.82 | CCR1 (0.39) | CCR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL1840636 | 0.82 | HPGD (0.41) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL1842532 | 0.82 | KDM4E (0.36) | CCR1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL1838903 | 0.80 | BRPF1 (0.45) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL1845558 | 0.80 | CCR1 (0.40) | CCR1KDM4EALDH1A1MAPTBRPF1 | |
| SCHEMBL1844082 | 0.80 | ALDH1A1 (0.45) | CCR1KDM4EALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091944-B1 | SUBSTITUTED BICYCLOCARBOXYAMIDE COMPOUNDS | PFIZER (US) | 2011-05-18 | — | — | EP | claimed |