Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 4/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 4/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18399446 | 0.94 | HSP90AA1 (0.60) | HSP90AA1SIRT1HTTLMNAABCC9 | |
| SCHEMBL18400610 | 0.84 | HTT (0.48) | HSP90AA1SIRT1HTTSMN1; SMN2LMNA | |
| SCHEMBL18399441 | 0.78 | NR1I2 (0.48) | HSP90AA1HTTLMNAESR1ESR2 | |
| SCHEMBL18400613 | 0.77 | HSP90AA1 (0.43) | HSP90AA1SIRT1SMN1; SMN2ABCC9ABCC8 | |
| SCHEMBL10002090 | 0.76 | SMN1; SMN2 (0.44) | HSP90AA1HTTSMN1; SMN2LMNAMAPT | |
| SCHEMBL18399461 | 0.75 | ESR1 (0.52) | HSP90AA1HTTLMNAESR1ESR2 | |
| SCHEMBL18399442 | 0.75 | ESR1 (0.52) | HSP90AA1HTTLMNAESR1ESR2 | |
| SCHEMBL10002086 | 0.75 | PDK1 (0.40) | HSP90AA1HTTSMN1; SMN2LMNAMAPT | |
| SCHEMBL18399448 | 0.75 | HSD11B1 (0.50) | HSP90AA1HTTLMNAPKMABCC9 | |
| SCHEMBL18399451 | 0.74 | ESR1 (0.56) | HSP90AA1HTTLMNAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088666-A1 | Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-03-30 | — | — | US | disclosed |
| US-9550711-B2 | Fluorine-containing polymerizable monomer and polymer compound using same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-01-24 | — | — | US | disclosed |