Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 5/20 | 0.45 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.45 |
| ▸ | KCNJ8 | Q15842 | 5/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.43 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18399458 | 0.94 | HSP90AA1 (0.55) | HSP90AA1SIRT1ABCC9ABCC8KCNJ11 | |
| SCHEMBL18400613 | 0.82 | HSP90AA1 (0.43) | HSP90AA1SIRT1ABCC9ABCC8KCNJ11 | |
| SCHEMBL10002090 | 0.81 | SMN1; SMN2 (0.44) | HSP90AA1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL18399443 | 0.78 | HSP90AA1 (0.48) | HSP90AA1NR1I2ALDH1A1LMNACYP2C9 | |
| SCHEMBL18400610 | 0.77 | HTT (0.48) | HSP90AA1SIRT1ABCC9ABCC8KCNJ11 | |
| SCHEMBL10002086 | 0.76 | PDK1 (0.40) | HSP90AA1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL18399450 | 0.75 | ESR1 (0.52) | HSP90AA1NR1I2ALDH1A1LMNACYP2C9 | |
| SCHEMBL18399449 | 0.75 | HSD11B1 (0.51) | HSP90AA1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL10428425 | 0.75 | SIRT1 (0.54) | HSP90AA1SIRT1ABCC9ABCC8KCNJ11 | |
| SCHEMBL18399455 | 0.74 | ALDH1A1 (0.46) | HSP90AA1NR1I2ALDH1A1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088666-A1 | Fluorine-Containing Polymerizable Monomer and Polymer Compound Using Same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-03-30 | — | — | US | disclosed |
| US-9550711-B2 | Fluorine-containing polymerizable monomer and polymer compound using same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2017-01-24 | — | — | US | disclosed |