Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517092 | 0.88 | HPGD (0.62) | ALOX15HPGDCYP1A2MAPTMEN1 | |
| SCHEMBL11180219 | 0.80 | ALDH1A1 (0.58) | ALOX15HPGDCYP1A2MAPTMEN1 | |
| SCHEMBL541086 | 0.79 | HNF4A (0.51) | MAPTALDH1A1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5885064 | 0.77 | HPGD (0.68) | ALOX15HPGDCYP1A2MAPTKMT2A | |
| SCHEMBL9778247 | 0.76 | HPGD (0.59) | ALOX15HPGDCYP1A2MAPTALDH1A1 | |
| SCHEMBL7445832 | 0.75 | HNF4A (0.51) | MEN1KMT2AALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL28085560 | 0.75 | HNF4A (0.51) | HPGDMEN1KMT2AALDH1A1CHRNB2 | |
| SCHEMBL8088437 | 0.75 | HNF4A (0.51) | MEN1KMT2AALDH1A1LMNACHRNB2 | |
| SCHEMBL7978017 | 0.73 | HPGD (0.68) | ALOX15HPGDCYP1A2MAPTMEN1 | |
| SCHEMBL3459359 | 0.73 | CA1 (0.70) | ALOX15HPGDCYP1A2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551412-B1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DISEASES RELATED TO NEUROTROPHINES | MINERVA PATENTS SA (LU) | 2011-05-04 | — | — | EP | claimed |