Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.62 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.62 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840255 | 0.88 | ALOX15 (0.56) | HPGDCHRNB2CHRNA4CYP1A2CHRNB4 | |
| SCHEMBL5885064 | 0.81 | HPGD (0.68) | HPGDCYP1A2MAPTALOX15KMT2A | |
| SCHEMBL11007801 | 0.81 | CHRNB2 (0.72) | CHRNB2CHRNA4CHRNB4CHRNA3KMT2A | |
| SCHEMBL7217604 | 0.78 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNB4CHRNA3KMT2A | |
| SCHEMBL7978017 | 0.78 | HPGD (0.68) | HPGDCYP1A2MAPTALOX15KMT2A | |
| SCHEMBL8841217 | 0.78 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNB4CHRNA3KMT2A | |
| SCHEMBL3459359 | 0.78 | CA1 (0.70) | HPGDCYP1A2MAPTALOX15KMT2A | |
| SCHEMBL1649572 | 0.78 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNB4CHRNA3KMT2A | |
| SCHEMBL7212801 | 0.78 | HPGD (0.51) | HPGDCYP1A2MAPTALOX15KMT2A | |
| SCHEMBL9778247 | 0.77 | HPGD (0.59) | HPGDCYP1A2MAPTALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | claimed |
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | claimed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | claimed |