Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 13/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839909 | 0.87 | BRS3 (0.48) | BRS3AGTR1AGTR2 | |
| SCHEMBL6054864 | 0.81 | RIPK1 (0.51) | — | |
| SCHEMBL1839256 | 0.80 | ESR2 (0.39) | BRS3 | |
| SCHEMBL1839836 | 0.77 | BRS3 (0.59) | BRS3 | |
| SCHEMBL1844573 | 0.73 | SOS1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL1839643 | 0.70 | TAAR1 (0.48) | BRS3AGTR1AGTR2 | |
| SCHEMBL2547080 | 0.70 | MYC (0.56) | — | |
| SCHEMBL9553365 | 0.69 | BRS3 (0.53) | BRS3 | |
| SCHEMBL3514348 | 0.69 | BRS3 (0.66) | BRS3 | |
| SCHEMBL22227471 | 0.69 | LTB4R2 (0.49) | BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321281-A2 | ANTI INFLAMMATORY COMPOUNDS | Elder Pharmaceuticals Ltd (IN) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010029576-A2 | ANTI INFLAMMATORY COMPOUNDS | ELDER PHARMACEUTICALS LTD. (IN) | 2010-03-18 | — | — | WO | disclosed |