Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 8/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840296 | 0.87 | BRS3 (0.48) | BRS3AGTR1AGTR2 | |
| SCHEMBL1839256 | 0.76 | ESR2 (0.39) | BRS3 | |
| SCHEMBL2548788 | 0.73 | ALDH1A1 (0.51) | BRS3SLC6A3SLC6A4BDKRB1AGTR1 | |
| SCHEMBL9488402 | 0.73 | SLC6A3 (0.63) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL14326964 | 0.71 | SLC6A3 (0.69) | BRS3SLC6A3SLC6A4SLC6A2BDKRB1 | |
| SCHEMBL3112718 | 0.71 | SLC6A3 (0.69) | BRS3SLC6A3SLC6A4SLC6A2BDKRB1 | |
| SCHEMBL29979869 | 0.71 | SLC6A3 (0.69) | BRS3SLC6A3SLC6A4SLC6A2BDKRB1 | |
| SCHEMBL16669003 | 0.71 | MEN1 (0.43) | SLC6A3RNASEH1 | |
| SCHEMBL2642187 | 0.70 | SLC6A3 (0.67) | BRS3SLC6A3SLC6A4SLC6A2BDKRB1 | |
| Bromide SCHEMBL8670915 | 0.69 | SLC6A3 (0.65) | BRS3SLC6A3SLC6A4SLC6A2BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321281-A2 | ANTI INFLAMMATORY COMPOUNDS | Elder Pharmaceuticals Ltd (IN) | 2011-05-18 | — | — | EP | claimed |
| WO-2010029576-A2 | ANTI INFLAMMATORY COMPOUNDS | ELDER PHARMACEUTICALS LTD. (IN) | 2010-03-18 | — | — | WO | claimed |