Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320753 | 0.86 | KIF11 (0.59) | KIF11CYP2A6ALDH1A1PTPN5CYP19A1 | |
| SCHEMBL516605 | 0.82 | KIF11 (0.55) | KIF11CYP2A6ALDH1A1PTPN5CYP19A1 | |
| SCHEMBL22303438 | 0.82 | KIF11 (0.55) | KIF11CYP2A6ALDH1A1PTPN5CYP19A1 | |
| SCHEMBL524351 | 0.80 | KIF11 (0.86) | KIF11CYP2A6ALDH1A1PTPN5CYP19A1 | |
| SCHEMBL20149636 | 0.80 | KIF11 (0.64) | KIF11CYP2A6ALDH1A1PTPN5CYP19A1 | |
| SCHEMBL29244941 | 0.80 | KIF11 (0.64) | KIF11CYP2A6ALDH1A1PTPN5CYP19A1 | |
| SCHEMBL678344 | 0.80 | KIF11 (0.64) | KIF11CYP2A6ALDH1A1PTPN5CYP19A1 | |
| SCHEMBL69655 | 0.80 | KIF11 (0.86) | KIF11CYP2A6ALDH1A1PTPN5CYP19A1 | |
| SCHEMBL2998724 | 0.80 | KIF11 (0.64) | KIF11CYP2A6ALDH1A1PTPN5CYP19A1 | |
| SCHEMBL12299036 | 0.79 | TSHR (0.40) | KIF11ALDH1A1TSHRCYP3A4NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113559802-B | Device and method for synthesizing drug intermediate trifluoromethyl substituted aromatic compound | 北京六合宁远医药科技股份有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-113559802-A | Device and method for synthesizing drug intermediate trifluoromethyl substituted aromatic compound | 北京六合宁远医药科技股份有限公司 | 2021-10-29 | — | — | CN | claimed |
| WO-2026090589-A1 | HETEROCYCLIC HBS1L DEGRADERS | TANGO THERAPEUTICS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-4635568-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA Pharmaceuticals Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-3672954-B1 | COMPOUNDS, SALTS THEREOF AND THEIR USE FOR THE TREATMENT OF DISEASES | ACADIA PHARM INC (US) | 2025-08-13 | — | — | EP | disclosed |
| US-20250197385-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARM INC (US) | 2025-06-19 | — | — | US | disclosed |
| US-12139477-B2 | Compounds, salts thereof and methods for treatment of diseases | ACADIA PHARMACEUTICALS INC. (US) | 2024-11-12 | — | — | US | disclosed |
| CN-117466803-A | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-111132976-B | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-113559802-B | Device and method for synthesizing drug intermediate trifluoromethyl substituted aromatic compound | 北京六合宁远医药科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| US-20220298151-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2022-09-22 | — | — | US | disclosed |
| EP-2921489-A1 | 2-PYRIDONE COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2015-09-23 | — | — | EP | disclosed |
| US-20150239796-A1 | ONE POT SYNTHESIS OF 18F LABELEDTRIFLUOROMETHYLATED COMPOUNDS WITH DIFLUORO(IODO)METHANE | UNIVERSITY OF OSLO (NO) | 2015-08-27 | — | — | US | disclosed |
| CN-104768944-A | 2-pyridone compound | TAISHO PHARMACEUTICAL CO LTD | 2015-07-08 | — | — | CN | disclosed |
| WO-2014077235-A1 | 2-PYRIDONE COMPOUND | 大正製薬株式会社 (JP) | 2014-05-22 | — | — | WO | disclosed |
| US-7960419-B2 | Substituted carboxamides | ELI LILLY AND COMPANY (US) | 2011-06-14 | — | — | US | disclosed |
| EP-2076502-B1 | SUBSTITUTED CARBOXAMIDES AS GROUP I METABOTROPIC RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2011-05-18 | — | — | EP | disclosed |
| US-20090182025-A1 | SUBSTITUTED CARBOXAMIDES | ELI LILLY AND COMPANY | 2009-07-16 | — | — | US | disclosed |
| EP-2076502-A2 | SUBSTITUTED CARBOXAMIDES AS GROUP I METABOTROPIC RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008103185-A2 | SUBSTITUTED CARBOXAMIDES AS GROUP I METABOTROPIC RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298151-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | SLC10A1, CYP27A1, CYP11B2 | KIF11 3906/4885CYP2A6 283/4885ALDH1A1 240/4885 |
| US-12139477-B2 | Compounds, salts thereof and methods for treatment of diseases | SLC10A1, CYP27A1, CYP11B2 | KIF11 3906/4885CYP2A6 283/4885ALDH1A1 240/4885 |
| US-20250197385-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | SLC10A1, CYP27A1, CYP11B2 | KIF11 3906/4885CYP2A6 283/4885ALDH1A1 240/4885 |
| US-20090182025-A1 | SUBSTITUTED CARBOXAMIDES | CNR2, TRPV1, CNR1 | KIF11 3536/4885CYP2A6 269/4885ALDH1A1 831/4885 |
| US-20150239796-A1 | ONE POT SYNTHESIS OF 18F LABELEDTRIFLUOROMETHYLATED COMPOUNDS WITH DIFLUORO(IODO)METHANE | FLI1, AFF1, CYP2F1 | KIF11 827/4885CYP2A6 263/4885ALDH1A1 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.