Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18404162 | 0.87 | ALDH1A1 (0.50) | POLBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL6668682 | 0.85 | ALDH1A1 (0.46) | POLBKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL6667674 | 0.85 | MEN1 (0.51) | POLBKMT2AMEN1SMN1; SMN2TACR3 | |
| SCHEMBL6671131 | 0.83 | POLB (0.47) | POLBKMT2AMEN1MAPT | |
| SCHEMBL6668894 | 0.83 | HTT (0.47) | POLBKMT2AMEN1TACR3MAPT | |
| SCHEMBL24036553 | 0.83 | THRB (0.47) | POLBKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7176606 | 0.83 | MEN1 (0.50) | POLBKMT2AMEN1SMN1; SMN2TACR3 | |
| SCHEMBL7365092 | 0.82 | ALDH1A1 (0.50) | KMT2AMEN1MAPTHTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7176273 | 0.82 | POLB (0.46) | POLBKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7170943 | 0.82 | HTT (0.46) | POLBKMT2AMEN1TACR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534138-B1 | 1,2,3-TRIAZOLE-BASED PEPTIDOMIMETIC INTEGRIN INHIBITORS FOR THE DIAGNOSIS AND THERAPY OF TUMORS | UNIVERSITA' DEGLI STUDI DI FIRENZE (IT) | 2017-01-25 | — | — | EP | disclosed |