Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | CTSA | P10619 | 5/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667674 | 0.89 | MEN1 (0.51) | ALDH1A1SMN1; SMN2POLBCTSAMEN1 | |
| SCHEMBL6668894 | 0.88 | HTT (0.47) | ALDH1A1LMNAPOLBCTSAMEN1 | |
| SCHEMBL6671131 | 0.88 | POLB (0.47) | POLBCTSAUTS2RMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7176606 | 0.88 | MEN1 (0.50) | SMN1; SMN2POLBCTSAUTS2RMEN1 | |
| Hydrochloric Acid SCHEMBL7170943 | 0.87 | HTT (0.46) | ALDH1A1LMNAPOLBCTSAMEN1 | |
| Hydrochloric Acid SCHEMBL7176273 | 0.87 | POLB (0.46) | POLBCTSAUTS2RKMT2AMAPT | |
| SCHEMBL7362926 | 0.86 | KEAP1 (0.53) | ALDH1A1LMNASMN1; SMN2POLBCTSA | |
| SCHEMBL6671512 | 0.85 | THRB (0.49) | ALDH1A1POLBUTS2RMEN1KMT2A | |
| SCHEMBL18404686 | 0.85 | POLB (0.43) | ALDH1A1LMNASMN1; SMN2POLBMEN1 | |
| SCHEMBL18404162 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2POLBCTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153014-B1 | BETA-ALANINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-09-22 | — | — | EP | disclosed |