SCHEMBL184047

SCHEMBL184047

C=C(C)C(=O)Nc1cccc(OCC2CO2)c1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.55
ALDH1A1 P00352 3/20 0.55
TP53 P04637 2/20 0.55
CYP3A4 P08684 1/20 0.55
TSHR P16473 1/20 0.55
HIF1A Q16665 1/20 0.55
TDP1 Q9NUW8 2/20 0.50
NR1H4 Q96RI1 2/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 2/20 0.43
THRB P10828 1/20 0.43
GLA P06280 1/20 0.43
MAPK1 P28482 1/20 0.41
LMNA P02545 1/20 0.41
AHR P35869 1/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28644970 0.87 SMN1; SMN2 (0.60) SMN1; SMN2ALDH1A1TP53CYP3A4TSHR
SCHEMBL7092798 0.87 SMN1; SMN2 (0.60) SMN1; SMN2ALDH1A1TP53CYP3A4TSHR
SCHEMBL29847483 0.87 SMN1; SMN2 (0.60) SMN1; SMN2ALDH1A1TP53CYP3A4TSHR
SCHEMBL183895 0.85 RAB9A (0.50) SMN1; SMN2ALDH1A1TP53CYP3A4TSHR
SCHEMBL15821380 0.83 SMN1; SMN2 (0.62) SMN1; SMN2ALDH1A1TP53CYP3A4TSHR
Methacrylic Acid SCHEMBL2019863 0.82 ALDH1A1 (0.69) SMN1; SMN2ALDH1A1TP53CYP3A4TSHR
Methacrylic Acid SCHEMBL8650788 0.82 ALDH1A1 (0.69) SMN1; SMN2ALDH1A1TP53CYP3A4TSHR
SCHEMBL184081 0.81 TP53 (0.56) SMN1; SMN2ALDH1A1TP53CYP3A4TSHR
SCHEMBL11643118 0.81 TP53 (0.56) SMN1; SMN2ALDH1A1TP53CYP3A4TSHR
SCHEMBL8476750 0.80 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1TDP1NR1H4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3510108-A1 WATERBORNE COPOLYMER DISPERSIONS WITH IMPROVED WET SCRUB RESISTANCE Celanese International Corporation (US) 2019-07-17 EP claimed
US-9920483-B2 Copolymer dispersions and their use in paper-coating formulations CELANESE SALES GERMANY GMBH (DE) 2018-03-20 US claimed
WO-2018049034-A1 WATERBORNE COPOLYMER DISPERSIONS WITH IMPROVED WET SCRUB RESISTANCE CELANESE INTERNATIONAL CORPORATION (US) 2018-03-15 WO claimed
US-20160153148-A1 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS CELANESE EMULSIONS GMBH (DE) 2016-06-02 US claimed
EP-3011106-A2 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS Celanese Sales Germany GmbH (DE) 2016-04-27 EP claimed
CN-105431589-A Copolymer dispersions and their use in paper-coating formulations CELANESE SALES GERMANY GMBH 2016-03-23 CN claimed
WO-2014204777-A2 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS CELANESE EMULSIONS GMBH (DE) 2014-12-24 WO claimed
WO-2014204779-A1 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS CELANESE EMULSIONS GMBH (DE) 2014-12-24 WO claimed
US-5710211-A REACTION OF POLYMER WITH COMPOUND HAVING A THIOL OR THIOESTER AND HYDROLYSIS TO FORM VINYL ALCOHOL KURARAY CO., LTD. (JP) 1998-01-20 US claimed
EP-3660214-B1 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS CELANESE SALES GERMANY GMBH (DE) 2024-09-04 EP disclosed
EP-3660214-A1 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS Celanese Sales Germany GmbH (DE) 2020-06-03 EP disclosed
EP-3510108-A1 WATERBORNE COPOLYMER DISPERSIONS WITH IMPROVED WET SCRUB RESISTANCE Celanese International Corporation (US) 2019-07-17 EP disclosed
US-10118978-B2 Vinyl alcohol polymer and production method thereof, additive for drilling mud, drilling mud, additive for drilling cement slurry, and drilling cement slurry KURARAY CO., LTD. (JP) 2018-11-06 US disclosed
US-9920483-B2 Copolymer dispersions and their use in paper-coating formulations CELANESE SALES GERMANY GMBH (DE) 2018-03-20 US disclosed
WO-2009000379-A1 CROSSLINKABLE POLYMER DISPERSIONS, COATING COMPOSITIONS COMPRISING THEM AND USE THEREOF CELANESE EMULSIONS GMBH (DE) 2008-12-31 WO disclosed
WO-2008110242-A1 CROSS-LINKABLE POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF CELANESE EMULSIONS GMBH (DE) 2008-09-18 WO disclosed
CN-1965027-A Aqueous dispersion, composition and coating agent for paper KURARAY CO (JP) 2007-05-16 CN disclosed
EP-0757060-B1 Process for producing vinyl alcohol polymer KURARAY CO (JP) 1999-10-20 EP disclosed
US-5710211-A REACTION OF POLYMER WITH COMPOUND HAVING A THIOL OR THIOESTER AND HYDROLYSIS TO FORM VINYL ALCOHOL KURARAY CO., LTD. (JP) 1998-01-20 US disclosed
EP-0757060-A2 Process for producing vinyl alcohol polymer KURARAY CO., LTD. (JP) 1997-02-05 EP disclosed