SCHEMBL184081

SCHEMBL184081

C=CC(=O)Nc1cccc(OCC2CO2)c1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.56
ALDH1A1 P00352 1/20 0.56
CYP3A4 P08684 1/20 0.56
TSHR P16473 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HIF1A Q16665 1/20 0.56
BTK Q06187 2/20 0.49
TGM2 P21980 3/20 0.48
MAP2K7 O14733 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ITK Q08881 6/20 0.46
EGFR P00533 4/20 0.46
TIPARP Q7Z3E1 1/20 0.46
KDM1A O60341 3/20 0.45
NR1H4 Q96RI1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183985 0.84 TGM2 (0.54) TP53ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL15821380 0.84 SMN1; SMN2 (0.62) TP53ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL7092798 0.83 SMN1; SMN2 (0.60) TP53ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL28644970 0.83 SMN1; SMN2 (0.60) TP53ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL29847483 0.83 SMN1; SMN2 (0.60) TP53ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL184047 0.81 SMN1; SMN2 (0.55) TP53ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL11643118 0.80 TP53 (0.56) TP53ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL1433889 0.79 ALDH1A1 (0.67) TP53ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL1352236 0.79 TGM2 (0.61) TGM2TDP1ITKEGFR
SCHEMBL5037362 0.79 MAP2K7 (0.59) ALDH1A1SMN1; SMN2TGM2MAP2K7ITK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3510108-A1 WATERBORNE COPOLYMER DISPERSIONS WITH IMPROVED WET SCRUB RESISTANCE Celanese International Corporation (US) 2019-07-17 EP claimed
US-9920483-B2 Copolymer dispersions and their use in paper-coating formulations CELANESE SALES GERMANY GMBH (DE) 2018-03-20 US claimed
US-20180072912-A1 WATERBORNE COPOLYMER DISPERSIONS WITH IMPROVED WET SCRUB RESISTANCE CELANESE INTERNATIONAL CORPORATION 2018-03-15 US claimed
WO-2018049034-A1 WATERBORNE COPOLYMER DISPERSIONS WITH IMPROVED WET SCRUB RESISTANCE CELANESE INTERNATIONAL CORPORATION (US) 2018-03-15 WO claimed
US-20160153148-A1 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS CELANESE EMULSIONS GMBH (DE) 2016-06-02 US claimed
EP-3011106-A2 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS Celanese Sales Germany GmbH (DE) 2016-04-27 EP claimed
CN-105431589-A Copolymer dispersions and their use in paper-coating formulations CELANESE SALES GERMANY GMBH 2016-03-23 CN claimed
WO-2014204779-A1 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS CELANESE EMULSIONS GMBH (DE) 2014-12-24 WO claimed
WO-2014204777-A2 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS CELANESE EMULSIONS GMBH (DE) 2014-12-24 WO claimed
US-5710211-A REACTION OF POLYMER WITH COMPOUND HAVING A THIOL OR THIOESTER AND HYDROLYSIS TO FORM VINYL ALCOHOL KURARAY CO., LTD. (JP) 1998-01-20 US claimed
JP-3264571-A None JP disclosed
EP-3660214-B1 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS CELANESE SALES GERMANY GMBH (DE) 2024-09-04 EP disclosed
EP-3660214-A1 COPOLYMER DISPERSIONS AND THEIR USE IN PAPER-COATING FORMULATIONS Celanese Sales Germany GmbH (DE) 2020-06-03 EP disclosed
EP-3510108-A1 WATERBORNE COPOLYMER DISPERSIONS WITH IMPROVED WET SCRUB RESISTANCE Celanese International Corporation (US) 2019-07-17 EP disclosed
US-10118978-B2 Vinyl alcohol polymer and production method thereof, additive for drilling mud, drilling mud, additive for drilling cement slurry, and drilling cement slurry KURARAY CO., LTD. (JP) 2018-11-06 US disclosed
CN-1965027-A Aqueous dispersion, composition and coating agent for paper KURARAY CO (JP) 2007-05-16 CN disclosed
EP-0757060-B1 Process for producing vinyl alcohol polymer KURARAY CO (JP) 1999-10-20 EP disclosed
US-5710211-A REACTION OF POLYMER WITH COMPOUND HAVING A THIOL OR THIOESTER AND HYDROLYSIS TO FORM VINYL ALCOHOL KURARAY CO., LTD. (JP) 1998-01-20 US disclosed
EP-0757060-A2 Process for producing vinyl alcohol polymer KURARAY CO., LTD. (JP) 1997-02-05 EP disclosed
JP-H03264571-A EPOXY-BASED COMPOUND, PRODUCTION THEREOF AND CURED RESIN OBTAINED FROM SAME COMPOUND TEIJIN LTD 1991-11-25 JP disclosed