Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.59 |
| ▸ | CTSS | P25774 | 4/20 | 0.59 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.58 |
| ▸ | PRKCG | P05129 | 4/20 | 0.48 |
| ▸ | PRKCB | P05771 | 4/20 | 0.48 |
| ▸ | PRKCA | P17252 | 4/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | PRKACG | P22612 | 1/20 | 0.48 |
| ▸ | PRKACB | P22694 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18406927 | 0.95 | CTSL (0.64) | CTSLCTSSPIN1PRKCGPRKCB | |
| SCHEMBL18406917 | 0.95 | CTSL (0.64) | CTSLCTSSPIN1PRKCGPRKCB | |
| SCHEMBL18405734 | 0.88 | CTSL (0.45) | CTSLCTSSPIN1PRKCGPRKCB | |
| SCHEMBL18405704 | 0.87 | CTSL (0.44) | CTSLCTSSPIN1CA2CA7 | |
| SCHEMBL18405715 | 0.86 | CTSL (0.43) | CTSLCTSSPIN1CA2CA7 | |
| SCHEMBL18405737 | 0.86 | CTSL (0.43) | CTSLCTSSPIN1CA2CA7 | |
| SCHEMBL18405721 | 0.85 | CTSL (0.43) | CTSLCTSSPIN1CA2CA7 | |
| SCHEMBL18405713 | 0.84 | CA12 (0.44) | CTSLCTSSPIN1PRKCGPRKCB | |
| SCHEMBL18405689 | 0.84 | SMN1; SMN2 (0.51) | MMP2MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL18406922 | 0.84 | CTSL (0.47) | CTSLCTSSPIN1PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170020837-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2017-01-26 | — | — | US | disclosed |
| US-20170020837-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170020837-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | FH, FPGS, APC | CTSL 2900/4885CTSS 1115/4885PIN1 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.