SCHEMBL18406153

SCHEMBL18406153

Cc1ccc(C)c2cc3c(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cccc3cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP1A2 P05177 4/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ENPP3 O14638 1/20 0.35
ENPP1 P22413 1/20 0.35
TLR8 Q9NR97 1/20 0.35
CYP2A6 P11509 2/20 0.35
FLT3 P36888 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33
TUBB2A Q13885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30005900 0.90 L3MBTL1 (0.50) KDM4EATML3MBTL1ALDH1A1HPGD
SCHEMBL18395044 0.90 L3MBTL1 (0.50) KDM4EATML3MBTL1ALDH1A1HPGD
SCHEMBL18548892 0.89 L3MBTL1 (0.46) KDM4EATML3MBTL1ALDH1A1HPGD
SCHEMBL18394742 0.89 L3MBTL1 (0.48) KDM4EATML3MBTL1CYP1A2ALDH1A1
SCHEMBL30005762 0.89 L3MBTL1 (0.48) KDM4EATML3MBTL1CYP1A2ALDH1A1
SCHEMBL18406155 0.89 L3MBTL1 (0.48) KDM4EATML3MBTL1ALDH1A1HPGD
SCHEMBL18566835 0.87 L3MBTL1 (0.44) KDM4EATML3MBTL1ALDH1A1HPGD
SCHEMBL9890871 0.87 L3MBTL1 (0.47) KDM4EATML3MBTL1ALDH1A1HPGD
SCHEMBL18566827 0.86 KDM4E (0.38) KDM4EATML3MBTL1CYP1A2ALDH1A1
SCHEMBL18566819 0.86 KDM4E (0.38) KDM4EATML3MBTL1CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180026207-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-01-25 US disclosed
US-20170025621-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Lighting System SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180026207-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device FLI1, ESR1, TRPA1 KDM4E 2870/4885ATM 3814/4885L3MBTL1 68/4885
US-20170025621-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Lighting System LAGE3, TEAD1, TEAD4 KDM4E 2301/4885ATM 1385/4885L3MBTL1 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.