Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54695 | 0.78 | KMT2A (0.54) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL27931982 | 0.78 | TDP1 (0.58) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL38726 | 0.75 | TDP1 (0.61) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11904537 | 0.75 | TDP1 (0.61) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL55477 | 0.75 | TDP1 (0.47) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6229622 | 0.75 | TDP1 (0.51) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL20144700 | 0.74 | TDP1 (0.45) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7138575 | 0.74 | ALDH1A1 (0.65) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2851741 | 0.74 | NPSR1 (0.51) | TDP1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4892995 | 0.74 | TDP1 (0.68) | TDP1MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253742-B1 | SYNTHETIC PROCESS FOR PREPARING 2-((2-ETHOXY-2-OXOETHYL)(METHYL)AMINO)-2-OXOETHYL 5-TETRADECYLOXY)FURAN-2-CARBOXYLATE | DERMIRA INC (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-3253743-B1 | SYNTHETIC PROCESS FOR PREPARING 2-FUROIC ACID DERIVATIVES | DERMIRA INC (US) | 2019-05-15 | — | — | EP | disclosed |
| US-9975867-B2 | Synthetic process for preparing 2-furoic acid derivatives | DERMIRA INC. (US) | 2018-05-22 | — | — | US | disclosed |
| WO-2018022797-A1 | DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE | DERMIRA INC. (US) | 2018-02-01 | — | — | WO | disclosed |
| US-20180028487-A1 | DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE | DERMIRA, INC. | 2018-02-01 | — | — | US | disclosed |
| US-9745277-B2 | Synthetic process for preparing 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate | DERMIRA INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-20170022176-A1 | SYNTHETIC PROCESS FOR PREPARING 2-((2-ETHOXY-2-OXOETHYL)(METHYL)AMINO)-2-OXOETHYL 5-TETRADECYLOXY)FURAN-2-CARBOXYLATE | DERMIRA, INC. | 2017-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028487-A1 | DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE | CUTA, CYP1A2, DPM1 | TDP1 2071/4885MEN1 3030/4885KMT2A 339/4885 |
| US-20170022176-A1 | SYNTHETIC PROCESS FOR PREPARING 2-((2-ETHOXY-2-OXOETHYL)(METHYL)AMINO)-2-OXOETHYL 5-TETRADECYLOXY)FURAN-2-CARBOXYLATE | TET2, TET3, TET1 | TDP1 3718/4885MEN1 941/4885KMT2A 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.