Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | MYLK | Q15746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29850622 | 0.77 | SNCA (0.86) | SNCAMAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL1208152 | 0.77 | SNCA (0.86) | SNCAMAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL21752000 | 0.74 | SNCA (1.00) | SNCAMAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL19398391 | 0.74 | SNCA (0.76) | SNCAMAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL21751995 | 0.69 | SNCA (1.00) | SNCAMAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL17591100 | 0.69 | SNCA (0.71) | SNCAMAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL18408660 | 0.65 | SNCA (0.58) | SNCAMAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL21096869 | 0.64 | SNCA (0.48) | SNCAMAPTMAPK1SMN1; SMN2LMNA | |
| SCHEMBL21771119 | 0.63 | SNCA (0.71) | SNCAMAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL8226390 | 0.63 | SNCA (0.56) | SNCAMAPTKDM4EMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121169-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WisTa Laboratories Ltd. (SG) | 2017-01-25 | — | — | EP | disclosed |