Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1208152 | 0.79 | SNCA (0.86) | SNCAMAPTKDM4ESIRT2LMNA | |
| SCHEMBL29850622 | 0.79 | SNCA (0.86) | SNCAMAPTKDM4ESIRT2LMNA | |
| SCHEMBL19398391 | 0.73 | SNCA (0.76) | SNCAMAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL21752000 | 0.73 | SNCA (1.00) | SNCAMAPTKDM4ESIRT2LMNA | |
| SCHEMBL21751995 | 0.71 | SNCA (1.00) | SNCAMAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL17591100 | 0.71 | SNCA (0.71) | SNCAMAPTKDM4ESIRT2LMNA | |
| SCHEMBL21771119 | 0.67 | SNCA (0.71) | SNCAMAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL8226390 | 0.65 | SNCA (0.56) | SNCAMAPTKDM4ESIRT2LMNA | |
| SCHEMBL8226386 | 0.65 | SNCA (0.78) | SNCAMAPTSIRT2GAARAB9A | |
| SCHEMBL18408642 | 0.65 | SNCA (0.57) | SNCAMAPTKDM4ESIRT2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121169-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WisTa Laboratories Ltd. (SG) | 2017-01-25 | — | — | EP | disclosed |