Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | HTR1D | P28221 | 4/20 | 0.48 |
| ▸ | HTR1B | P28222 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | NMT2 | O60551 | 1/20 | 0.47 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12936456 | 0.87 | HTR1D (0.65) | APPHTR1DHTR1BHTR1AHTR6 | |
| SCHEMBL9526594 | 0.78 | HTR1D (0.77) | APPHTR1DHTR1BHTR1ANMT2 | |
| Hydrochloric Acid SCHEMBL9526972 | 0.77 | HTR1D (0.76) | APPHTR1DHTR1BHTR1ANMT2 | |
| SCHEMBL9526685 | 0.76 | HTR1D (0.62) | APPHTR1DHTR1BHTR1ANMT2 | |
| SCHEMBL9375123 | 0.74 | HTR6 (0.52) | HTR1DHTR1BHTR1AHTR2CHTR6 | |
| SCHEMBL8916861 | 0.72 | NMT2 (0.48) | APPHTR1DHTR1BHTR1ANMT2 | |
| SCHEMBL27290426 | 0.72 | NMT2 (0.55) | APPHTR1DHTR1BHTR1ANMT2 | |
| SCHEMBL3832948 | 0.71 | HTR2C (0.62) | APPHTR1DHTR1BNMT2NMT1 | |
| SCHEMBL7459828 | 0.71 | HTR2C (0.62) | APPHTR1DHTR1BNMT2NMT1 | |
| SCHEMBL9764521 | 0.71 | HTR1D (0.66) | APPHTR1DHTR1BHTR1ANMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017013031-A1 | 5-HYDROXYTRYPTAMINE 1B RECEPTOR-STIMULATING AGENT FOR USE AS A PROMOTER OF SATELLITE CELLS SELF-RENEWAL AND/OR DIFFERENTIATION | INSTITUT PASTEUR (FR) | 2017-01-26 | — | — | WO | disclosed |