Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18418520 | 1.00 | TLR2 (0.51) | TLR2ALDH1A1MAPTLMNAMDM2 | |
| SCHEMBL23728631 | 0.87 | CASP3 (0.44) | ALDH1A1MAPTLMNAMDM2HPGD | |
| SCHEMBL15281424 | 0.87 | CASP3 (0.44) | ALDH1A1MAPTLMNAMDM2HPGD | |
| SCHEMBL872752 | 0.87 | CASP3 (0.44) | ALDH1A1MAPTLMNAMDM2HPGD | |
| SCHEMBL30410248 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL25695323 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL30013082 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL15106634 | 0.84 | BRD4 (0.41) | ALDH1A1MAPTLMNAMDM2HPGD | |
| SCHEMBL15182047 | 0.84 | BRD4 (0.41) | ALDH1A1MAPTLMNAMDM2HPGD | |
| SCHEMBL2641803 | 0.84 | BRD4 (0.41) | ALDH1A1MAPTLMNAMDM2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170029437-A1 | Compositions and Methods for Treating Neoplasia, Inflammatory Disease and Other Disorders | NATIONAL INSTITUTES OF HEALTH- DIRECTOR DEITR | 2017-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029437-A1 | Compositions and Methods for Treating Neoplasia, Inflammatory Disease and Other Disorders | BRPF3, EP300, BRD3 | TLR2 1942/4885ALDH1A1 3670/4885MAPT 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.