Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842400 | 0.93 | KMT2A (0.58) | POLBMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL1844054 | 0.90 | SMN1; SMN2 (0.62) | POLBMAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL14441803 | 0.87 | POLB (0.45) | POLBMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL1847914 | 0.86 | KMT2A (0.43) | POLBMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL1844314 | 0.84 | KMT2A (0.44) | POLBMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL26374397 | 0.84 | POLB (0.43) | POLBMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL2402749 | 0.82 | LMNA (0.61) | POLBKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1844640 | 0.81 | TMEM97 (0.46) | POLBMAPTKMT2AALDH1A1GAA | |
| SCHEMBL14003290 | 0.80 | ALDH1A1 (0.41) | POLBMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL27781639 | 0.78 | POLB (0.38) | POLBMAPTLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467969-B1 | DNA MINOR GROOVE BINDING COMPOUNDS | UNIV STRATHCLYDE (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-7700765-B2 | DNA minor groove binding compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2010-04-20 | — | — | US | disclosed |
| US-20070117760-A1 | Dna minor groove binding compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117760-A1 | Dna minor groove binding compounds | PCNA, POLL, POLM | POLB 4/4885MAPT 1908/4885KMT2A 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.