Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GNG2 | P59768 | 1/20 | 0.32 |
| ▸ | GNB1 | P62873 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1264191 | 0.84 | MAPT (0.46) | RAB9ANPC1NLRP3L3MBTL1BRD4 | |
| Hydrochloric Acid SCHEMBL14871697 | 0.84 | MAPT (0.46) | RAB9ANPC1NLRP3L3MBTL1BRD4 | |
| SCHEMBL6158097 | 0.82 | RAB9A (0.56) | RAB9ANPC1NLRP3L3MBTL1BRD4 | |
| SCHEMBL19052327 | 0.70 | NPC1 (0.64) | RAB9ANPC1NLRP3L3MBTL1BRD4 | |
| SCHEMBL23844 | 0.69 | MAPT (0.55) | RAB9ANPC1L3MBTL1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL519644 | 0.67 | NPC1 (0.56) | RAB9ANPC1NLRP3L3MBTL1BRD4 | |
| SCHEMBL9275601 | 0.67 | MEN1 (0.61) | RAB9ANPC1NLRP3L3MBTL1BRD4 | |
| SCHEMBL9279444 | 0.67 | NPC1 (0.56) | RAB9ANPC1NLRP3L3MBTL1BRD4 | |
| SCHEMBL13593612 | 0.67 | NPC1 (0.41) | RAB9ANPC1NLRP3L3MBTL1BRD4 | |
| Bromide SCHEMBL11796180 | 0.66 | MAPT (0.47) | RAB9ANPC1NLRP3L3MBTL1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017019817-A1 | METHODS AND COMPOSITIONS FOR TARGETED THERAPEUTICS | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-02-02 | — | — | WO | disclosed |
| WO-2017019830-A1 | METHODS AND COMPOSITIONS FOR TARGETED THERAPEUTICS | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-02-02 | — | — | WO | disclosed |