Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | NQO2 | P16083 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15987437 | 0.81 | KDM4E (0.50) | MAPTKMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL6714495 | 0.78 | — | — | |
| SCHEMBL11227486 | 0.78 | TDP1 (0.50) | L3MBTL1KDM4ETDP1 | |
| SCHEMBL194246 | 0.78 | MAPT (0.39) | MAPTNQO2KMT2AMEN1NPC1 | |
| SCHEMBL27027 | 0.78 | ALDH1A1 (0.62) | MAPTNQO2KMT2APOLBMEN1 | |
| SCHEMBL24814 | 0.78 | ALDH1A1 (0.62) | MAPTNQO2KMT2APOLBMEN1 | |
| Phenazine SCHEMBL2291618 | 0.78 | MAPT (0.92) | MAPTNQO2KMT2APOLBMEN1 | |
| SCHEMBL6700746 | 0.76 | MAPT (0.65) | MAPTNQO2KMT2APOLBMEN1 | |
| SCHEMBL8719387 | 0.74 | KMT2A (0.47) | MAPTKMT2APOLBMEN1NPC1 | |
| Phenazine SCHEMBL29356959 | 0.74 | MAPT (1.00) | MAPTNQO2KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2209 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49118-E1 | Material for organic electroluminescence device and electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2022-06-28 | — | — | US | claimed |
| CN-114057711-A | Anthracene ketone spiro derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2022-02-18 | — | — | CN | claimed |
| CN-107556298-B | Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element | 出光兴产株式会社 | 2021-12-21 | — | — | CN | claimed |
| WO-2021078217-A1 | TETRACENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国科学院化学研究所 | 2021-04-29 | — | — | WO | claimed |
| CN-112694388-A | Naphthacene derivative and preparation method and application thereof | 中国科学院化学研究所 | 2021-04-23 | — | — | CN | claimed |
| CN-112390811-A | Dithia-anthrone derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2021-02-23 | — | — | CN | claimed |
| US-10550203-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2020-02-04 | — | — | US | claimed |
| CN-110551054-A | maleimide derivative, and preparation method and application thereof | TECHNICAL INST PHYSICS & CHEMISTRY CAS | 2019-12-10 | — | — | CN | claimed |
| US-10283717-B2 | Organic electroluminescent device using aryl amine derivative containing heterocycle | IDEMITSU KOSAN CO., LTD. (JP) | 2019-05-07 | — | — | US | claimed |
| US-20180319905-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-11-08 | — | — | US | claimed |
| EP-1785425-A2 | Novel 1,4-diazabicycloalkane derivatives, their preparation and use | NeuroSearch A/S (DK) | 2007-05-16 | — | — | EP | claimed |
| US-20060122172-A1 | Novel 1,4-diazabicycloalkane derivatives, their preparation and use | DANPET AB (SE) | 2006-06-08 | — | — | US | claimed |
| CN-1684965-A | Novel 1,4-diazabicycloalkane derivatives, their preparation and use | NEUROSEARCH AS (DK) | 2005-10-19 | — | — | CN | claimed |
| EP-1551835-A1 | NOVEL 1,4-DIAZABICYCLOALKANE DERIVATIVES, THEIR PREPARATION AND USE | NeuroSearch A/S (DK) | 2005-07-13 | — | — | EP | claimed |
| WO-2004029053-A1 | NOVEL 1,4-DIAZABICYCLOALKANE DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 2004-04-08 | — | — | WO | claimed |
| EP-0751944-B1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2000-12-20 | — | — | EP | claimed |
| US-5955481-A | Pyridine type thiazolidines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-21 | — | — | US | claimed |
| CN-1144526-A | Thiazolidines and oxazolidines substituted by pyridine ring and their use a hypoglycemic agents | NISSAN CHEMICAL IND LTD (JP) | 1997-03-05 | — | — | CN | claimed |
| EP-0751944-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-01-08 | — | — | EP | claimed |
| WO-1995026347-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-05 | — | — | WO | claimed |