Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 15/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055039 | 0.90 | NPC1 (0.68) | NPC1ALDH1A1CYP2D6CYP2C19APP | |
| SCHEMBL223680 | 0.84 | ALDH1A1 (0.61) | NPC1ALDH1A1CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL29816629 | 0.84 | ALDH1A1 (0.61) | NPC1ALDH1A1CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL510090 | 0.81 | NPC1 (0.63) | NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL31473741 | 0.81 | NPC1 (0.58) | NPC1ALDH1A1CYP2D6CYP2C19APP | |
| SCHEMBL31544077 | 0.81 | NPC1 (0.63) | NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL1680866 | 0.81 | NPC1 (0.58) | NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL510167 | 0.81 | NPC1 (0.58) | NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL21054861 | 0.81 | NPC1 (0.58) | NPC1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL510400 | 0.81 | NPC1 (0.58) | NPC1ALDH1A1CYP2D6CYP2C19APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581565-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | Beijing Zhibo Bio-Medical Technology Co., Ltd. (CN) | 2019-12-18 | — | — | EP | disclosed |
| US-20170037008-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | ZHANG ZHIYONG (CN) | 2017-02-09 | — | — | US | disclosed |
| CN-103724207-B | Phenylbenzyl ether derivative and its preparation method and application | 北京智博高科生物技术有限公司 | 2016-07-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037008-A1 | PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | APP, PSEN1, PSEN2 | NPC1 69/4885ALDH1A1 3616/4885CYP2D6 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.