Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223680 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP2C19NPC1CYP2D6LTA4H | |
| Formaldehyde SCHEMBL29285221 | 0.94 | CYP2C19 (0.56) | ALDH1A1CYP2C19NPC1CYP2D6LTA4H | |
| SCHEMBL10055039 | 0.93 | NPC1 (0.68) | ALDH1A1CYP2C19NPC1CYP2D6LTA4H | |
| SCHEMBL6130101 | 0.88 | NPC1 (0.58) | ALDH1A1CYP2C19NPC1CYP2D6LTA4H | |
| SCHEMBL510167 | 0.84 | NPC1 (0.58) | ALDH1A1CYP2C19NPC1CYP2D6LTA4H | |
| SCHEMBL510090 | 0.84 | NPC1 (0.63) | ALDH1A1CYP2C19NPC1CYP2D6LTA4H | |
| SCHEMBL510400 | 0.84 | NPC1 (0.58) | ALDH1A1CYP2C19NPC1CYP2D6LMNA | |
| SCHEMBL21054861 | 0.84 | NPC1 (0.58) | ALDH1A1CYP2C19NPC1CYP2D6LTA4H | |
| SCHEMBL18429765 | 0.84 | NPC1 (0.58) | ALDH1A1CYP2C19NPC1CYP2D6CYP3A4 | |
| SCHEMBL31473741 | 0.84 | NPC1 (0.58) | ALDH1A1CYP2C19NPC1CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500572-B1 | CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION | UNIV BRISTOL (GB) | 2022-10-26 | — | — | EP | claimed |
| US-20240254093-A1 | GPR35 Agonist Compounds | NXERA PHARMA UK LIMITED (GB) | 2024-08-01 | — | — | US | disclosed |
| US-20240180886-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-06-06 | — | — | US | disclosed |
| US-20240182490-A1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2024-06-06 | — | — | US | disclosed |
| US-11753376-B2 | Benzyloxy pyridine derivatives and uses thereof | AUTOTAC INC. (KR) | 2023-09-12 | — | — | US | disclosed |
| US-20220315601-A1 | BROMODOMAIN INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2022-10-06 | — | — | US | disclosed |
| US-20220298113-A1 | BENZYLOXY PYRIDINE DERIVATIVES AND USES THEREOF | AUTOTAC INC. (KR) | 2022-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254093-A1 | GPR35 Agonist Compounds | GPR35, GPR119, GPR68 | ALDH1A1 1962/4885CYP2C19 2608/4885NPC1 493/4885 |
| US-20240182490-A1 | BROMODOMAIN INHIBITORS | BRD3, EP300, BRPF3 | ALDH1A1 3316/4885CYP2C19 4857/4885NPC1 2992/4885 |
| US-11753376-B2 | Benzyloxy pyridine derivatives and uses thereof | SQSTM1, ATG7, BECN1 | ALDH1A1 3915/4885CYP2C19 3729/4885NPC1 601/4885 |
| US-20220315601-A1 | BROMODOMAIN INHIBITORS | BRD3, EP300, BRPF3 | ALDH1A1 3316/4885CYP2C19 4857/4885NPC1 2992/4885 |
| US-20240180886-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | PTPN2, PTPN22, PTPN1 | ALDH1A1 3561/4885CYP2C19 1459/4885NPC1 2974/4885 |
| US-20220298113-A1 | BENZYLOXY PYRIDINE DERIVATIVES AND USES THEREOF | SQSTM1, ATG7, BECN1 | ALDH1A1 3915/4885CYP2C19 3729/4885NPC1 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.