SCHEMBL223680

SCHEMBL223680

c1ccc(COc2ccccn2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
CYP2C19 P33261 2/20 0.61
NPC1 O15118 1/20 0.61
CYP2D6 P10635 1/20 0.61
LTA4H P09960 1/20 0.52
MAPK14 Q16539 1/20 0.52
GABRA5 P31644 2/20 0.47
TSHR P16473 2/20 0.46
PKM P14618 1/20 0.46
CYP3A4 P08684 1/20 0.46
LMNA P02545 2/20 0.45
CYP1A2 P05177 1/20 0.45
PTGS1 P23219 1/20 0.45
SLC6A2 P23975 1/20 0.45
PTGS2 P35354 1/20 0.45
SLC6A3 Q01959 1/20 0.45
HIF1A Q16665 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
MAPT P10636 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29816629 1.00 ALDH1A1 (0.61) ALDH1A1CYP2C19NPC1CYP2D6LTA4H
Formaldehyde SCHEMBL29285221 0.94 CYP2C19 (0.56) ALDH1A1CYP2C19NPC1CYP2D6LTA4H
SCHEMBL10055039 0.93 NPC1 (0.68) ALDH1A1CYP2C19NPC1CYP2D6LTA4H
SCHEMBL6130101 0.88 NPC1 (0.58) ALDH1A1CYP2C19NPC1CYP2D6LTA4H
SCHEMBL510167 0.84 NPC1 (0.58) ALDH1A1CYP2C19NPC1CYP2D6LTA4H
SCHEMBL510090 0.84 NPC1 (0.63) ALDH1A1CYP2C19NPC1CYP2D6LTA4H
SCHEMBL510400 0.84 NPC1 (0.58) ALDH1A1CYP2C19NPC1CYP2D6LMNA
SCHEMBL21054861 0.84 NPC1 (0.58) ALDH1A1CYP2C19NPC1CYP2D6LTA4H
SCHEMBL18429765 0.84 NPC1 (0.58) ALDH1A1CYP2C19NPC1CYP2D6CYP3A4
SCHEMBL31473741 0.84 NPC1 (0.58) ALDH1A1CYP2C19NPC1CYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912388-A Preparation method of high-purity and high-yield benzyloxypyridine compound 天津辰欣药物研究有限公司 2025-05-02 CN claimed
US-20240287073-A1 4-SUBSTITUED CYTISINE ANALOGUES THE UNIVERSITY OF BRISTOL (GB) 2024-08-29 US claimed
US-11905287-B2 4-substitued cytisine analogues THE UNIVERSITY OF BRISTOL (GB) 2024-02-20 US claimed
US-20230203038-A1 4-SUBSTITUED CYTISINE ANALOGUES THE UNIVERSITY OF BRISTOL (GB) 2023-06-29 US claimed
US-11667638-B2 4-substitued cytisine analogues THE UNIVERSITY OF BRISTOL 2023-06-06 US claimed
EP-4112620-A1 CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION The University of Bristol (GB) 2023-01-04 EP claimed
EP-3500572-B1 CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION UNIV BRISTOL (GB) 2022-10-26 EP claimed
CN-113387799-B Preparation method of gamma, gamma-diaryl ester or gamma, gamma-triaryl ester compound and product thereof 南京工业大学 2021-12-21 CN claimed
US-20200172544-A1 COMPOUNDS THE UNIVERSITY OF BRISTOL (GB) 2020-06-04 US claimed
CN-110088106-A Compound 布里斯托大学 2019-08-02 CN claimed
EP-3500572-A2 CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION The University Of Bristol (GB) 2019-06-26 EP claimed
WO-2018033742-A2 COMPOUNDS THE UNIVERSITY OF BRISTOL (GB) 2018-02-22 WO claimed
US-7754909-B1 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis The Florida State University Research Foundation, Inc. (US) 2010-07-13 US claimed
EP-0885194-B1 PYRIDYL-PHENYL- AND BENZYLETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES AND FOR CONTROLLING ANIMAL PESTS BASF AG (DE) 2002-10-16 EP claimed
US-6114363-A ACTIVITY AGAINST A BROAD SPECTRUM OF PHYTOPATHOGENIC FUNGI; COMPOUNDS SUCH AS N-METHYL-E-2-METHOXYIMINO-2-((2-(3-CHLORO-5-(PROP-1-EN-3-OXIMINOETH-1' -YL)PYRIDIN-2-YL))OXYMETHYL) PHENYL)ACETAMIDE BASF AKTIENGESELLSCHAFT (DE) 2000-09-05 US claimed
US-5202334-A Pyrazolo[1,5-a]pyridine compounds, and production and use thereof SENJU PHARMACEUTICAL CO., LTD. (JP) 1993-04-13 US claimed
EP-0433001-A1 Insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-06-19 EP claimed
CN-1042144-A Pesticidal compound ICI PLC (GB) 1990-05-16 CN claimed
EP-0356029-A2 Insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-02-28 EP claimed
JP-9059254-A None JP disclosed
JP-9059253-A None JP disclosed
EP-4705291-A1 IKK-ALPHA INHIBITORS Cancer Research Technology Limited (GB) 2026-03-11 EP disclosed
CN-119912388-B Preparation method of high-purity and high-yield benzyloxypyridine compound 天津辰欣药物研究有限公司 2025-08-08 CN disclosed
CN-119912388-B Preparation method of high-purity and high-yield benzyloxypyridine compound 天津辰欣药物研究有限公司 2025-08-08 CN disclosed
CN-119912388-A Preparation method of high-purity and high-yield benzyloxypyridine compound 天津辰欣药物研究有限公司 2025-05-02 CN disclosed
CN-119912388-A Preparation method of high-purity and high-yield benzyloxypyridine compound 天津辰欣药物研究有限公司 2025-05-02 CN disclosed
CN-119912388-A Preparation method of high-purity and high-yield benzyloxypyridine compound 天津辰欣药物研究有限公司 2025-05-02 CN disclosed
WO-2024228035-A1 IKK-ALPHA INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2024-11-07 WO disclosed
US-20240287073-A1 4-SUBSTITUED CYTISINE ANALOGUES THE UNIVERSITY OF BRISTOL (GB) 2024-08-29 US disclosed
EP-3897655-B1 3BETA-(BENZYLOXY)-17ALPHA-METHYL-PREGN-5-EN-20-ONE FOR USE IN THE TREATMENT OF COGNITIVE DISORDERS AELIS FARMA (FR) 2024-07-17 EP disclosed
US-11905287-B2 4-substitued cytisine analogues THE UNIVERSITY OF BRISTOL (GB) 2024-02-20 US disclosed
WO-2023174449-A1 METHOD FOR PREPARING N-(3-CHLORO-4-(2-PYRIDYLMETHOXY)PHENYL)-2-CYANOACETAMIDE 安庆朗坤药业有限公司 2023-09-21 WO disclosed
US-11753376-B2 Benzyloxy pyridine derivatives and uses thereof AUTOTAC INC. (KR) 2023-09-12 US disclosed
US-11753376-B2 Benzyloxy pyridine derivatives and uses thereof AUTOTAC INC. (KR) 2023-09-12 US disclosed
US-20230270750-A1 CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-08-31 US disclosed
CN-116472267-A Butyrylcholinesterase reactivating agent 法兰西国由中央军队卫生服务局代表 2023-07-21 CN disclosed
CN-114736154-B Process for preparing N- (3-chloro-4- (2-pyridylmethoxy) phenyl) -2-cyanoacetamide 安庆朗坤药业有限公司 2023-07-21 CN disclosed
US-20230203038-A1 4-SUBSTITUED CYTISINE ANALOGUES THE UNIVERSITY OF BRISTOL (GB) 2023-06-29 US disclosed
EP-4188919-A1 CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS Etat Français représenté par la Direction Centrale Du Service de Santé des Armées (FR) 2023-06-07 EP disclosed
US-11667638-B2 4-substitued cytisine analogues THE UNIVERSITY OF BRISTOL 2023-06-06 US disclosed
CN-116194453-A Protein tyrosine phosphatase degrading agent and method of use thereof 卡里科生命科学有限责任公司 2023-05-30 CN disclosed
CN-111646908-B Method for preparing aromatic amine compound 宜昌尚诺德生物医药科技有限公司 2023-03-10 CN disclosed
CN-111732493-B Synthesis process of arylamine compound 宜昌尚诺德生物医药科技有限公司 2023-01-24 CN disclosed
US-20230002679-A1 COMPOUND AND LIQUID CRYSTAL COMPOSITION FUJIFILM CORPORATION (JP) 2023-01-05 US disclosed
EP-4112620-A1 CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION The University of Bristol (GB) 2023-01-04 EP disclosed
US-20220402873-A1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, AMELIORATING, OR TREATING PROTEINOPATHIES AUTOTAC INC. (KR) 2022-12-22 US disclosed
EP-3500572-B1 CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION UNIV BRISTOL (GB) 2022-10-26 EP disclosed
US-20220298113-A1 BENZYLOXY PYRIDINE DERIVATIVES AND USES THEREOF AUTOTAC INC. (KR) 2022-09-22 US disclosed
US-20220298113-A1 BENZYLOXY PYRIDINE DERIVATIVES AND USES THEREOF AUTOTAC INC. (KR) 2022-09-22 US disclosed
CN-114736154-A Preparation method of N- (3-chloro-4- (2-pyridylmethoxy) phenyl) -2-cyanoacetamide 安庆朗坤药业有限公司 2022-07-12 CN disclosed
US-11267800-B2 Cyclohexyl acid triazole azines as LPA antagonists BRISTOL-MYERS SQUIBB COMPANY (US) 2022-03-08 US disclosed
US-20220017562-A1 3beta-(benzyloxy)-17alpha-methyl-pregn-5-en-20-one for use in the treatment of cognitive disorders INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2022-01-20 US disclosed
CN-113480394-A Green synthesis method of alkylene fluorene 温州大学 2021-10-08 CN disclosed
CN-111732493-A Synthesis process of arylamine compound 宜昌尚诺德生物医药科技有限公司 2020-10-02 CN disclosed
CN-111646908-A Method for preparing aromatic amine compound 宜昌尚诺德生物医药科技有限公司 2020-09-11 CN disclosed
CN-109422771-B Hydrothermally stable anion pillared hybrid porous material and preparation method and application thereof 浙江大学 2020-07-24 CN disclosed
CN-106800493-B Method for reducing aromatic nitro group into aromatic amine 宜昌尚诺德生物医药科技有限公司 2020-06-30 CN disclosed
EP-3669876-A1 3BÉTA-(BENZYLOXY)-17ALPHA-METHYL-PREGN-5-EN-20-ONE FOR USE IN THE TREATMENT OF COGNITIVE DISORDERS Aelis Farma (FR) 2020-06-24 EP disclosed
US-20200172544-A1 COMPOUNDS THE UNIVERSITY OF BRISTOL (GB) 2020-06-04 US disclosed
US-20190345087-A1 BIO-STABLE CANNABINOID COMPOUNDS AND METHODS FOR ENHANCING THEIR PHYSIOLOGICAL CONCENTRATION TUATARA CAPITAL FUND I, L.P. 2019-11-14 US disclosed
CN-110444667-A A kind of preparation method of organic diode laminated film TAICANG BIQI NEW MATERIAL RES & DEVELOPMENT CO LTD 2019-11-12 CN disclosed
EP-3541772-A1 BIO-STABLE CANNABINOID COMPOUNDS AND METHODS FOR ENHANCING THEIR PHYSIOLOGICAL CONCENTRATION Teewinot Technologies Limited (IE) 2019-09-25 EP disclosed
US-10384997-B2 Bio-stable cannabinoid compounds and methods for enhancing their physiological concentration TEEWINOT TECHNOLOGIES LIMITED (IE) 2019-08-20 US disclosed
CN-110088106-A Compound 布里斯托大学 2019-08-02 CN disclosed
EP-3500572-A2 CYTISINE DERIVATIVES FOR THE TREATMENT OF ADDICTION The University Of Bristol (GB) 2019-06-26 EP disclosed
CN-109689652-A Fused heterocycle derivative, preparation method and its application medically 北京诺诚健华医药科技有限公司 2019-04-26 CN disclosed
US-10174021-B2 Substituted pyrazolo[1,5-A]pyridines and their use BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2019-01-08 US disclosed
CN-106008466-B Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases 艾伯维公司 2018-12-14 CN disclosed
US-10138117-B2 Aqueous formulations for removing metal hard mask and post-etch residue with Cu/W compatibility ENTEGRIS, INC. (US) 2018-11-27 US disclosed
US-20180201560-A1 BIO-STABLE CANNABINOID COMPOUNDS AND METHODS FOR ENHANCING THEIR PHYSIOLOGICAL CONCENTRATION TUATARA CAPITAL FUND I, L.P. 2018-07-19 US disclosed
WO-2018091551-A1 BIO-STABLE CANNABINOID COMPOUNDS AND METHODS FOR ENHANCING THEIR PHYSIOLOGICAL CONCENTRATION FULL SPECTRUM LABORATORIES LTD (IE) 2018-05-24 WO disclosed
US-20180057509-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES CO (US) 2018-03-01 US disclosed
WO-2018033742-A2 COMPOUNDS THE UNIVERSITY OF BRISTOL (GB) 2018-02-22 WO disclosed
CN-103214471-B The preparation method of compound with Na-dependent glucose transporter inhibitory activity 田边三菱制药株式会社 2018-02-06 CN disclosed
US-20170313700-A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINES AND IMIDAZO[1,2-A]PYRAZINES AND THEIR USE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-11-02 US disclosed
EP-3030562-B1 SUBSTITUTED PYRAZOLO[1,5-A]-PYRIDINE-3-CARBOXAMIDES AND USE THEREOF Bayer Pharma AG (DE) 2017-07-26 EP disclosed
US-20170088559-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES CO (US) 2017-03-30 US disclosed
CN-106397418-A APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE公司 2017-02-15 CN disclosed
US-9546184-B2 Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-01-17 US disclosed
CN-103380154-B Activator composition, its preparation and the purposes in catalysis thereof 阿尔比马尔公司 2016-08-24 CN disclosed
US-20160185595-A1 AQUEOUS FORMULATIONS FOR REMOVING METAL HARD MASK AND POST-ETCH RESIDUE WITH Cu/W COMPATIBILITY TRUIST BANK, AS NOTES COLLATERAL AGENT 2016-06-30 US disclosed
EP-2657229-B1 BENZYLOXYPYRIMIDINE DERIVATIVE, AGRICULTURAL/HORTICULTURAL INSECTICIDE COMPRISING SAID DERIVATIVE AND METHOD FOR USING THE SAME NIHON NOHYAKU CO LTD (JP) 2016-03-30 EP disclosed
US-20150307496-A1 NOVEL TRICYCLIC 3,4-DIHYDRO-2H-PYRIDO[1,2-a]PYRAZINE-1,6-DIONE DERIVATIVES AS GAMMA SECRETASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2015-10-29 US disclosed
US-20150266901-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES CO (US) 2015-09-24 US disclosed
CN-104854150-A Activator compositions, their preparation, and their use in catalysts ALBEMARLE CORP 2015-08-19 CN disclosed
US-8895574-B2 Benzyloxypyrimidine derivative, agricultural/ horticultural insecticide comprising derivative and method for using same NIHON NOHYAKU CO., LTD. (JP) 2014-11-25 US disclosed
CN-104140393-A Preparation method of aromatic ring/aromatic heterocycle tert-butyl alcohol ester compound TETRANOV BIOPHARM INC 2014-11-12 CN disclosed
WO-2014164767-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN FORMA THERAPEUTICS, INC. (US) 2014-10-09 WO disclosed
CN-103998432-A Bicyclic compounds TAKEDA PHARMACEUTICAL 2014-08-20 CN disclosed
US-8778963-B2 Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-07-15 US disclosed
EP-1846419-B1 Alkoxy-substituted thiazoloquinolines and thiazolonaphthyridines 3M INNOVATIVE PROPERTIES CO (US) 2014-04-16 EP disclosed
US-8673932-B2 Oxime substituted imidazo-containing compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-03-18 US disclosed
US-8598192-B2 Hydroxylamine substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-12-03 US disclosed
US-8580992-B1 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis The Florida State University Research Foundation, Inc. (US) 2013-11-12 US disclosed
EP-2657229-A1 BENZYLOXYPYRIMIDINE DERIVATIVE, AGRICULTURAL/HORTICULTURAL INSECTICIDE COMPRISING DERIVATIVE AND METHOD FOR USING SAME Nihon Nohyaku Co., Ltd. (JP) 2013-10-30 EP disclosed
US-20130267564-A1 BENZYLOXYPYRIMIDINE DERIVATIVE, AGRICULTURAL/ HORTICULTURAL INSECTICIDE COMPRISING DERIVATIVE AND METHOD FOR USING SAME NIHON NOHYAKU CO., LTD. (JP) 2013-10-10 US disclosed
US-8546383-B2 Chiral fused [1,2]imidazo[4,5-c] ring compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-10-01 US disclosed
CN-103068819-A Heterocyclic antiviral compounds HOFFMANN LA ROCHE 2013-04-24 CN disclosed
CN-102971305-A Heterocyclic antiviral compounds HOFFMANN LA ROCHE 2013-03-13 CN disclosed
US-8378102-B2 Oxime and hydroxylamine substituted thiazolo[4,5-c] ring compounds and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-02-19 US disclosed
US-8350034-B2 Substituted chiral fused [1,2]imidazo[4,5-C] ring compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-01-08 US disclosed
US-8334414-B2 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2012-12-18 US disclosed
CN-102803216-A Heterocyclic antiviral compounds HOFFMANN LA ROCHE 2012-11-28 CN disclosed
US-8273773-B2 Heterocyclic antiviral compounds ROCHE PALO ALTO LLC (US) 2012-09-25 US disclosed
US-20120232057-A1 CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY 2012-09-13 US disclosed
CN-101558095-B Propylene block copolymer SUMITOMO CO LTD 2012-09-05 CN disclosed
EP-1831221-B1 SUBSTITUTED CHIRAL FUSED 1,2 IMIDAZO 4,5-C RING COMPOUNDS 3M INNOVATIVE PROPERTIES CO (US) 2012-08-08 EP disclosed
EP-1831226-B1 CHIRAL TETRACYCLIC COMPOUNDS INDUCING INTERFERON BIOSYNTHESIS 3M INNOVATIVE PROPERTIES CO (US) 2012-08-08 EP disclosed
US-8207162-B2 Chiral fused [1,2]imidazo[4,5-c] ring compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-06-26 US disclosed
US-8188119-B2 Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same EISAI R&D MANAGEMENT CO., LTD (JP) 2012-05-29 US disclosed
EP-1789042-B1 1-ALKOXY 1H-IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2012-05-02 EP disclosed
US-8168792-B2 Heterocyclic antiviral compounds ROCHE PALO ALTO LLC (US) 2012-05-01 US disclosed
EP-2307372-B1 HETEROCYCLIC ANTIVIRAL COMPOUNDS HOFFMANN LA ROCHE (CH) 2012-04-25 EP disclosed
US-8158803-B2 Heterocyclic antiviral compounds ROCHE PALO ALTO LLC (US) 2012-04-17 US disclosed
EP-2421831-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS F. Hoffmann-La Roche AG (CH) 2012-02-29 EP disclosed
CN-102341382-A HETEROCYCLIC ANTIVIRAL COMPOUNDS HOFFMANN LA ROCHE 2012-02-01 CN disclosed
EP-2403844-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS F. Hoffmann-La Roche AG (CH) 2012-01-11 EP disclosed
US-8093390-B2 Substituted fused [1,2]imidazo[4,5-C] ring compounds and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-01-10 US disclosed
US-20120004213-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2012-01-05 US disclosed
US-20120004213-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2012-01-05 US disclosed
US-20120004213-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2012-01-05 US disclosed
US-20110293654-A1 SUBSTITUTED CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS 3M INNOVATIVE PROPERTIES COMANY 2011-12-01 US disclosed
US-8039463-B2 Piperazine derivatives as inhibitors of stearoyl-CoA desaturase FOREST LABORATORIES HOLDINGS LIMITED (BM) 2011-10-18 US disclosed
US-8039463-B2 Piperazine derivatives as inhibitors of stearoyl-CoA desaturase FOREST LABORATORIES HOLDINGS LIMITED (BM) 2011-10-18 US disclosed
US-8039463-B2 Piperazine derivatives as inhibitors of stearoyl-CoA desaturase FOREST LABORATORIES HOLDINGS LIMITED (BM) 2011-10-18 US disclosed
US-8034938-B2 Imidazo[4,5-c]quinolines, 6,7,8,9-tetrahydroimidazo[4,5-c]quinolines, imidazo[4,5-c]naphthyridines, and 6,7,8,9-tetrahydroimidazo[4,5-c]naphthyridines) with a CH( R1) group in the fused ring at 1-position of imidazo ring; modulate immune response, by induction of cytokine biosynthesis or other mechanism 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-10-11 US disclosed
US-8026366-B2 Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-09-27 US disclosed
US-8008531-B2 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis The Florida State University Research Foundation, Inc. (US) 2011-08-30 US disclosed
US-20110207725-A1 CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY 2011-08-25 US disclosed
US-7968563-B2 Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-06-28 US disclosed
CN-102099335-A Heterocyclic antiviral compounds HOFFMANN LA ROCHE 2011-06-15 CN disclosed
CN-101255217-B Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL CO 2011-05-25 CN disclosed
US-7943609-B2 Such as (tetrahydr)imidazo(4,5-c ) quinoline or naphthymidine; immunomoderators; induce cytokine biosynthesis in animals; anticancer agents; viricides 3M INNOVATIVE PROPRERTIES COMPANY (US) 2011-05-17 US disclosed
CN-102036666-A Novel piperazine derivatives as inhibitors of stearoyl-coA desaturase FOREST LAB HOLDINGS LTD 2011-04-27 CN disclosed
EP-2307372-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS F. Hoffmann-La Roche AG (CH) 2011-04-13 EP disclosed
EP-2307023-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE Forest Laboratories Holdings Limited (BM) 2011-04-13 EP disclosed
US-7915437-B2 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2011-03-29 US disclosed
US-7897767-B2 Oxime substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-03-01 US disclosed
US-20100324324-A1 Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis DUDLEY GREGORY 2010-12-23 US disclosed
US-20100324323-A1 Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis DUDLEY GREGORY 2010-12-23 US disclosed
WO-2010122082-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2010-10-28 WO disclosed
US-20100272677-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS LEE EUN KYUNG 2010-10-28 US disclosed
US-20100256383-A1 Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis DUDLEY GREGORY 2010-10-07 US disclosed
US-20100240693-A1 Oxime and Hydroxylamine Substituted Thiazolo [4,5-C] Ring Compounds and Methods COLEY PHARMACEUTICAL GROUP, INC (US) 2010-09-23 US disclosed
WO-2010100178-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2010-09-10 WO disclosed
US-20100226879-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS ABBOT SARAH C 2010-09-09 US disclosed
US-7754909-B1 Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis The Florida State University Research Foundation, Inc. (US) 2010-07-13 US disclosed
US-7713994-B2 Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo,1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihyro-3 (2H)-isoquinolones and methods of use thereof WYETH LLC (US) 2010-05-11 US disclosed
US-20100105737-A1 PYRIDINE DERIVATIVES SUBSTITUTED WITH HETEROCYCLIC RING AND gamma-GLUTAMYLAMINO GROUP, AND ANTIFUNGAL AGENTS CONTAINING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-04-29 US disclosed
US-20100069427-A9 Oxime and Hydroxylamine Substituted Imidazo[4,5-c] Ring Compounds and Methods COLEY PHARMACEUTICAL GROUP, INC. (US) 2010-03-18 US disclosed
WO-2010026075-A1 PYRIDINE DERIVATIVES AS INHIBITORS OF HIV-I REVERSE TRANSCRIPTASE F. HOFFMANN-LA ROCHE AG (CH) 2010-03-11 WO disclosed
CN-101668767-A Pyridine derivatives substituted with heterocyclic ring and phosphonoamino group and antifungal agent containing the same EISAI R&D MAN CO LTD 2010-03-10 CN disclosed
US-20100056535-A1 Inhibitors of HIV-1 reverse transcriptase ROCHE PALO ALTO LLC 2010-03-04 US disclosed
WO-2010010017-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2010-01-28 WO disclosed
US-20100021423-A1 Heterocyclic antiviral compounds ROCHE PALO ALTO LLC 2010-01-28 US disclosed
US-7648997-B2 Immunomodulators for inducing cytokine biosynthesis, for treatment of diseases including viral and neoplastic diseases; 1-[3-(Aminooxy)propyl]-2-propyl-1H-imidazo[4,5-c]quinolin-4-amine; N-[3-(4-Amino-2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)propoxy]cyclopropanecarboxamide COLEY PHARMACEUTICAL GROUP, INC. (US) 2010-01-19 US disclosed
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
CN-101558095-A Propylene block copolymer SUMITOMO CHEMICAL CO (JP) 2009-10-14 CN disclosed
WO-2009117659-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2009-09-24 WO disclosed
WO-2009117659-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2009-09-24 WO disclosed
US-20090239848-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2009-09-24 US disclosed
US-20090239848-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2009-09-24 US disclosed
US-20090239848-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2009-09-24 US disclosed
CN-101528702-A Quinoline compounds and methods of use ARRAY BIOPHARMA INC (US) 2009-09-09 CN disclosed
US-7579359-B2 1-alkoxy 1H-imidazo ring systems and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-08-25 US disclosed
EP-1653955-A4 HYDROXYLAMINE SUBSTITUTED IMIDAZO-CONTAINING COMPOUNDS 3M INNOVATIVE PROPERTIES CO (US) 2009-07-29 EP disclosed
EP-1789042-A4 1-ALKOXY 1H-IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2009-07-22 EP disclosed
EP-1682544-A4 HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS 3M INNOVATIVE PROPERTIES CO (US) 2009-05-06 EP disclosed
US-20090105295-A1 HYDROXYLAMINE SUBSTITUTED IMIDAZOQUINOLINES COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-04-23 US disclosed
US-20090062328-A1 Oxime and Hydroxylamine Substituted Imidazo[4,5-c] Ring Compounds and Methods COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-03-05 US disclosed
US-20090042925-A1 OXIME SUBSTITUTED IMIDAZOQUINOLINES COLEY PHARMACEUTICAL GROUP, INC. 2009-02-12 US disclosed
CN-101356159-A Substituted isoquinoline-1, 3(2H,4H) -diones, 1-thio-1, 4-dihydro-2H-isoquinoline-3-ones and 1, 4-dihydro-3 (2H) -isoquinolones and their use as kinase inhibitors WYETH CORP (US) 2009-01-28 CN disclosed
US-20090005371-A1 Substituted Fused [1,2]Imidazo[4,5-C] Ring Compounds and Methods 3M INNOVATIVE PROPERTIES COMPANY 2009-01-01 US disclosed
US-20090005376-A1 imidazonaphthyridines, imidazopyridines, imidazoquinolines, and imidazote-trahydroquinolines; immunomodulators for inducing cytokine biosynthesis; for treatment of viral and neoplastic diseases 3M INNOVATIVE PROPERTIES COMPANY 2009-01-01 US disclosed
US-20080318998-A1 Alkyloxy Substituted Thiazoloquinolines and Thiazolonaphthyridines COLEY PHARMACEUTICAL GROUP, INC. (US) 2008-12-25 US disclosed
CN-101330916-A Substituted imidazoquinolines, imidazonaphthyridines, and imidazopyridines, compositions, and methods thereof COLEY PHARMACEUTICAL INC (US) 2008-12-24 CN disclosed
EP-1831221-A4 SUBSTITUTED CHIRAL FUSED 1,2 IMIDAZO 4,5-C RING COMPOUNDS 3M INNOVATIVE PROPERTIES CO (US) 2008-11-05 EP disclosed
EP-1831226-A4 CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS 3M INNOVATIVE PROPERTIES CO (US) 2008-11-05 EP disclosed
CN-101300250-A Heterocyclic substituted pyridine derivative and antifungal agent containing the same EISAI R&D MAN CO LTD (JP) 2008-11-05 CN disclosed
US-20080269192-A1 Chiral Fused [1,2]Imidazo[4,5-C] Ring Compounds COLEY PHARMACEUTICAL GROUP, INC. (US) 2008-10-30 US disclosed
EP-1653914-A4 OXIME SUBSTITUTED IMIDAZO-CONTAINING COMPOUNDS 3M INNOVATIVE PROPERTIES CO (US) 2008-10-29 EP disclosed
EP-1685129-A4 OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS 3M INNOVATIVE PROPERTIES CO (US) 2008-10-22 EP disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed
EP-1968587-A1 SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS Coley Pharmaceutical, Inc. (US) 2008-09-17 EP disclosed
EP-1963273-A2 SUBSTITUTED ISOQUINOLINE-1,3(2H,4H)-DIONES, 1-THIOXO-1,4-DIHYDRO-2H-ISOQUINOLINE-3-ONES AND 1,4-DIHYDRO-3(2H)-ISOQUINOLONES AND USE THEREOF AS KINASE INHIBITORS Wyeth a Corporation of the State of Delaware (US) 2008-09-03 EP disclosed
CN-101255217-A Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL CO (JP) 2008-09-03 CN disclosed
US-20080114019-A1 Hydroxylamine Substituted Imidazoquinolines COLEY PHARMACEUTICAL GROUP, INC. (US) 2008-05-15 US disclosed
US-7371777-B2 Cyclic compound and PPAR agonist EISAI CO., LTD. (JP) 2008-05-13 US disclosed
US-20080085895-A1 Substituted Chiral Fused [1,2]Imidazo[4,5-C] Ring Compounds 3M INNOVATIVE PROPERTIES COMPANY 2008-04-10 US disclosed
US-20080085890-A1 Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo-1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihydro-3 (2H)-isoquinolones and methods of use thereof WYETH (US) 2008-04-10 US disclosed
EP-1877056-A2 OXIME AND HYDROXYLAMINE SUBSTITUTED THIAZOLOÝ4,5-C¨RING COMPOUNDS AND METHODS Coley Pharmaceutical Group, Inc. (US) 2008-01-16 EP disclosed
CN-101094670-A Oxime substituted imidazoquinolines 3M INNOVATIVE PROPERTIES CO (US) 2007-12-26 CN disclosed
US-7312334-B2 Method of preparing inhibitors phosphodiesterase-4 MERCK & CO. INC. (US) 2007-12-25 US disclosed
US-7312334-B2 Method of preparing inhibitors phosphodiesterase-4 MERCK & CO. INC. (US) 2007-12-25 US disclosed
WO-2007120121-A2 OXIME AND HYDROXYLAMINE SUBSTITUTED THIAZOLO[4,5-C] RING COMPOUNDS AND METHODS COLEY PHARMACEUTICAL GROUP, INC. (US) 2007-10-25 WO disclosed
EP-1845986-A2 SUBSTITUTED FUSED [1,2]IMIDAZO[4,5-C]RING COMPOUNDS AND METHODS Coley Pharmaceutical Group, Inc. (US) 2007-10-24 EP disclosed
EP-1846405-A2 OXIME AND HYDROXYLAMINE SUBSTITUTED IMIDAZO 4,5-C RING COMPOUNDS AND METHODS 3M Innovative Properties Company (US) 2007-10-24 EP disclosed
EP-1846419-A2 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-10-24 EP disclosed
EP-1831221-A2 SUBSTITUTED CHIRAL FUSED 1,2 IMIDAZO 4,5-C RING COMPOUNDS 3M Innovative Properties Company (US) 2007-09-12 EP disclosed
EP-1831226-A2 CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-12 EP disclosed
US-20070208052-A1 Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY 2007-09-06 US disclosed
US-7253178-B2 Carboxylic acids EISAI CO., LTD. (JP) 2007-08-07 US disclosed
CN-1328261-C Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2007-07-25 CN disclosed
CN-1326856-C Method of preparing inhibitors of phosphodiesterase-4 MERCK & CO INC (US) 2007-07-18 CN disclosed
WO-2007075468-A1 SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS COLEY PHARMACEUTICAL GROUP, INC. (US) 2007-07-05 WO disclosed
WO-2007075783-A2 SUBSTITUTED ISOQUINOLINE-1,3(2H,4H)-DIONES, 1-THIOXO-1,4-DIHYDRO-2H-ISOQUINOLINE-3-ONES AND 1,4-DIHYDRO-3(2H)-ISOQUINOLONES AND USE THEREOF AS KINASE INHIBITOR WYETH (US) 2007-07-05 WO disclosed
EP-1789042-A2 1-ALKOXY 1H-IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-30 EP disclosed
US-20070099901-A1 Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-03 US disclosed
US-20070066639-A1 Oxime substituted imidazoquinolines 3M INNOVATIVE PROPERTIES COMPANY 2007-03-22 US disclosed
CN-1905874-A Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines 3M INNOVATIVE PROPERTIES CO (US) 2007-01-31 CN disclosed
CN-1906193-A Oxime substituted imidazo ring compounds 3M INNOVATIVE PROPERTIES CO (US) 2007-01-31 CN disclosed
CN-1906192-A Hydroxylamine substituted imidazo ring compounds 3M INNOVATIVE PROPERTIES CO (US) 2007-01-31 CN disclosed
CN-1835750-A Oxime substituted imidazo-containing compounds 3M INNOVATIVE PROPERTIES CO (US) 2006-09-20 CN disclosed
WO-2006086449-A2 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES COLEY PHARMACEUTICAL GROUP, INC. (US) 2006-08-17 WO disclosed
WO-2006086633-A2 SUBSTITUTED FUSED [1,2]IMIDAZO[4,5-C] RING COMPOUNDS AND METHODS COLEY PHARMACEUTICAL GROUP, INC. (US) 2006-08-17 WO disclosed
WO-2006086634-A2 OXIME AND HYDROXYLAMINE SUBSTITUTED IMIDAZO[4,5-C] RING COMPOUNDS AND METHODS COLEY PHARMACEUTICAL GROUP, INC. (US) 2006-08-17 WO disclosed
WO-2006083440-A2 SUBSTITUTED CHIRAL FUSED [1,2]IMIDAZO[4,5-C] RING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-08-10 WO disclosed
EP-1686992-A2 HYDROXYLAMINE AND OXIME SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES 3M Innovative Properties Company (US) 2006-08-09 EP disclosed
EP-1685129-A2 OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS 3M Innovative Properties Company (US) 2006-08-02 EP disclosed
EP-1682544-A2 HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS 3M Innovative Properties Company (US) 2006-07-26 EP disclosed
WO-2006074003-A2 CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-07-13 WO disclosed
US-7067658-B2 Pyridino and pyrimidino pyrazinones BRISTOL-MYERS SQUIBB COMPANY (US) 2006-06-27 US disclosed
EP-1653914-A2 OXIME SUBSTITUTED IMIDAZO-CONTAINING COMPOUNDS 3M Innovative Properties Company (US) 2006-05-10 EP disclosed
EP-1653955-A2 HYDROXYLAMINE SUBSTITUTED IMIDAZO-CONTAINING COMPOUNDS 3M Innovative Properties Company (US) 2006-05-10 EP disclosed
EP-1638935-A1 NK1 ANTAGONIST Pfizer Products Inc. (US) 2006-03-29 EP disclosed
WO-2006028962-A2 1-ALKOXY 1H-IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-03-16 WO disclosed
CN-1738818-A Process for preparing phosphodiesterase-4 inhibitors MERCK & CO INC (US) 2006-02-22 CN disclosed
US-20060019981-A1 Method of preparing inhibitors phosphodiesterase-4 MERCK & CO., INC. 2006-01-26 US disclosed
WO-2006009826-A1 ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-01-26 WO disclosed
EP-1397359-B1 1-BIARYL-1,8-NAPTHYRIDIN-4-ONE PHOSPHODIESTERASE-4 INHIBITORS MERCK FROSST CANADA INC (CA) 2005-08-31 EP disclosed
EP-1565466-A2 METHOD OF PREPARING INHIBITORS OF PHOSPHODIESTERASE-4 Merck & Co., Inc. (US) 2005-08-24 EP disclosed
CN-1213658-C Pyridinecarboxamide derivative and pest control agent containing same as active ingredient MEIJI SEIKA KAISHA (JP) 2005-08-10 CN disclosed
CN-1636981-A Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2005-07-13 CN disclosed
US-6909002-B2 Method of preparing inhibitors of phosphodiesterase-4 MERCK & CO., INC. (US) 2005-06-21 US disclosed
WO-2005051324-A2 HYDROXYLAMINE AND OXIME SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-06-09 WO disclosed
WO-2005048933-A2 OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-06-02 WO disclosed
WO-2005048945-A2 HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-06-02 WO disclosed
CN-1204137-C Uracil compound and application thereof SUMITOMO CHEMICAL CO (JP) 2005-06-01 CN disclosed
WO-2005018551-A2 OXIME SUBSTITUTED IMIDAZO-CONTAINING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-03-03 WO disclosed
WO-2005018556-A2 HYDROXYLAMINE SUBSTITUTED IMIDAZO-CONTAINING COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-03-03 WO disclosed
US-20050043354-A1 NK1 antagonist PFIZER INC 2005-02-24 US disclosed
WO-2004110996-A1 NK1 ANTAGONIST PFIZER PRODUCTS INC. (US) 2004-12-23 WO disclosed
WO-2004048377-A2 METHOD OF PREPARING INHIBITORS OF PHOSPHODIESTERASE-4 MERCK & CO., INC. (US) 2004-06-10 WO disclosed
US-20040102472-A1 Method of preparing inhibitors of phosphodiesterase-4 MERCK & CO., INC. 2004-05-27 US disclosed
US-20040102472-A1 Method of preparing inhibitors of phosphodiesterase-4 MERCK & CO., INC. 2004-05-27 US disclosed
US-20040082784-A1 Pyridino and pyrimidino pyrazinones BRISTOL-MYERS SQUIBB PHARMA COMPANY 2004-04-29 US disclosed
WO-2004031189-A1 PYRIDINO AND PYRIMIDINO PYRAZINONES FOR TREATMENT OF ANXIETY AND DEPRESSION BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2004-04-15 WO disclosed
EP-1397359-A1 1-BIARYL-1,8-NAPTHYRIDIN-4-ONE PHOSPHODIESTERASE-4 INHIBITORS Merck Frosst Canada & Co. (CA) 2004-03-17 EP disclosed
US-6677351-B2 USEFUL IN TREATMENT OF ASTHMA AND INFLAMMATION MERCK FROSST CANADA & CO. (CA) 2004-01-13 US disclosed
US-6645976-B1 Nonpancreatic secretory phospholipase (sPLA2) supressors such as 2-(3-Benzyl-8-hydroxy-2-ethylindolizin-1-yl)acetamide, administered to control release of fatty acid and prevent the arachidonic acid cascade; septic shock ELI LILLY AND COMPANY 2003-11-11 US disclosed
US-6630488-B1 Quinolizinones as integrin inhibitors BIOCHEM PHARMA, INC. (CA) 2003-10-07 US disclosed
EP-0772596-B1 INDOLIZINE sPLA2 INHIBITORS LILLY CO ELI (US) 2003-10-01 EP disclosed
US-20030096829-A1 1-biaryl-1,8-naphthyridin-4-one phosphodiesterase-4 inhibitors MERCK FROSST CANADA LTD. (CA) 2003-05-22 US disclosed
WO-2002094823-A1 1-BIARYL-1,8-NAPTHYRIDIN-4-ONE PHOSPHODIESTERASE-4 INHIBITORS MERCK FROSST CANADA & CO. (CA) 2002-11-28 WO disclosed
CN-1083433-C 2, 6-disubstituted pyridines, process for their preparation, herbicidal compositions and their use SHELL INT RESEARCH (NL) 2002-04-24 CN disclosed
CN-1077792-C Pyridyl bisphosphonates for use as therapeutic agents LEIRAS OY (FI) 2002-01-16 CN disclosed
CN-1329596-A Pyridinecarboxamide derivative and pest control agent containing same as active ingredient MEIJI SEIKA KAISHA (JP) 2002-01-02 CN disclosed
CN-1316426-A Uracil compound and application thereof SUMITOMO CHEMICAL CO (JP) 2001-10-10 CN disclosed
EP-1115724-A1 QUINOLIZINONES AS INTEGRIN INHIBITORS Shire Biochem Inc. (CA) 2001-07-18 EP disclosed
CN-1268137-A Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders DU PONT PHARM CO (US) 2000-09-27 CN disclosed
US-6114363-A ACTIVITY AGAINST A BROAD SPECTRUM OF PHYTOPATHOGENIC FUNGI; COMPOUNDS SUCH AS N-METHYL-E-2-METHOXYIMINO-2-((2-(3-CHLORO-5-(PROP-1-EN-3-OXIMINOETH-1' -YL)PYRIDIN-2-YL))OXYMETHYL) PHENYL)ACETAMIDE BASF AKTIENGESELLSCHAFT (DE) 2000-09-05 US disclosed
US-6114363-A ACTIVITY AGAINST A BROAD SPECTRUM OF PHYTOPATHOGENIC FUNGI; COMPOUNDS SUCH AS N-METHYL-E-2-METHOXYIMINO-2-((2-(3-CHLORO-5-(PROP-1-EN-3-OXIMINOETH-1' -YL)PYRIDIN-2-YL))OXYMETHYL) PHENYL)ACETAMIDE BASF AKTIENGESELLSCHAFT (DE) 2000-09-05 US disclosed
WO-2000017197-A1 QUINOLIZINONES AS INTEGRIN INHIBITORS BIOCHEM PHARMA INC. (US) 2000-03-30 WO disclosed
EP-0772596-A4 INDOLIZINE sPLA2 INHIBITORS LILLY CO ELI (US) 1999-01-13 EP disclosed
CN-1039183-C 2, 6-substituted pyridine herbicides SHELL INT RESEARCH (NL) 1998-07-22 CN disclosed
US-5691277-A REACTING A 2,6-DIHALOGENOPYRIDINE WITH A META SUBSTITUTED PHENOL KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-11-25 US disclosed
EP-0692474-B1 2- (unsubstituted or substituted) (benzyloxy or phenoxy)-4-substituted-6-(meta-substituted phenoxy) pyridine, process for producing the same, and herbicidal composition KUREHA CHEMICAL IND CO LTD (JP) 1997-10-29 EP disclosed
CN-1158121-A Indolizine sPLA2Inhibitors LILLY CO ELI (US) 1997-08-27 CN disclosed
EP-0772596-A1 INDOLIZINE sPLA2 INHIBITORS ELI LILLY AND COMPANY (US) 1997-05-14 EP disclosed
CN-1149830-A Pyridylbisphosphonates for use as therapeutical agent LEIRAS OY (FI) 1997-05-14 CN disclosed
JP-H0959253-A PRODUCTION OF 2-ARALKYLOXYPYRIDINES SAGAMI CHEM RES CENTER 1997-03-04 JP disclosed
JP-H0959254-A PRODUCTION OF 2-HYDROXYPYRIDINES AND/OR 2(1H)-PYRIDONES SAGAMI CHEM RES CENTER 1997-03-04 JP disclosed
CN-1122596-A Herbicidal heterocyclic-substituted pyridines SHELL INT RESEARCH (NL) 1996-05-15 CN disclosed
EP-0467721-B1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO (JP) 1996-03-27 EP disclosed
WO-1996003383-A1 INDOLIZINE sPLA2 INHIBITORS ELI LILLY AND COMPANY (US) 1996-02-08 WO disclosed
EP-0692474-A1 2- (unsubstituted or substituted) (benzyloxy or phenoxy)-4-substituted-6-(meta-substituted phenoxy) pyridine, process for producing the same, and herbicidal composition KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-17 EP disclosed
US-5480580-A COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY MITSUBISHI RAYON COMPANY LTD. (JP) 1996-01-02 US disclosed
CN-1079220-A 2, 6-substituted pyridine herbicides SHELL INT RESEARCH (NL) 1993-12-08 CN disclosed
US-5185251-A Treatment of HIV and AIDS MERCK & CO., INC. (US) 1993-02-09 US disclosed
US-5137886-A Agriculture IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-08-11 US disclosed
EP-0467721-A1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD (JP) 1992-01-22 EP disclosed
EP-0433001-A1 Insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-06-19 EP disclosed
US-4987141-A DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-22 US disclosed
US-4931452-A N-cyanomethyl-2-pyridinone insecticides THE DOW CHEMICAL COMPANY (US) 1990-06-05 US disclosed
CN-1042144-A Pesticidal compound ICI PLC (GB) 1990-05-16 CN disclosed
EP-0356029-A2 Insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-02-28 EP disclosed
CN-1034715-A N-cyanogen methyl-2-pyridinone insecticides DOW CHEMICAL CO (US) 1989-08-16 CN disclosed
US-4839369-A ANTIINFLAMMATORY AGENTS; ANTIALLERGENS RORER PHARMACEUTICAL CORPORATION (US) 1989-06-13 US disclosed
WO-1989004301-A1 N-CYANOMETHYL-2-PYRIDINONE INSECTICIDES THE DOW CHEMICAL COMPANY (US) 1989-05-18 WO disclosed
EP-0316185-A2 N-cyanomethyl-2-pyridinone insecticides THE DOW CHEMICAL COMPANY (US) 1989-05-17 EP disclosed
EP-0120670-B1 IRON III COMPLEXES OF HYDROXYPYRIDONES, AND THEIR PHARMACEUTICAL COMPOSITIONS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1988-12-21 EP disclosed
US-4728668-A Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments USV PHARMACEUTICAL CORPORATION (US) 1988-03-01 US disclosed
US-4725619-A Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments USV PHARMACEUTICAL CORPORATION (US) 1988-02-16 US disclosed
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EP-0200101-A2 Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments USV PHARMACEUTICAL CORPORATION (US) 1986-11-05 EP disclosed
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EP-0061379-B1 PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THERAPEUTIC PREPARATIONS SYNTHELABO (FR) 1985-10-02 EP disclosed
EP-0061379-B1 PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THERAPEUTIC PREPARATIONS SYNTHELABO (FR) 1985-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (50 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105737-A1 PYRIDINE DERIVATIVES SUBSTITUTED WITH HETEROCYCLIC RING AND gamma-GLUTAMYLAMINO GROUP, AND ANTIFUNGAL AGENTS CONTAINING SAME ASNS, ERG28, GLUL ALDH1A1 1834/4885CYP2C19 442/4885NPC1 350/4885
US-20150266901-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES IL2, IFNG, TSLP ALDH1A1 624/4885CYP2C19 1984/4885NPC1 2273/4885
US-20040102472-A1 Method of preparing inhibitors of phosphodiesterase-4 PDE4B, PDE4A, PDE5A ALDH1A1 558/4885CYP2C19 107/4885NPC1 3077/4885
US-20100056535-A1 Inhibitors of HIV-1 reverse transcriptase QTRT1, NQO2, QTRT2 ALDH1A1 301/4885CYP2C19 1567/4885NPC1 836/4885
US-10384997-B2 Bio-stable cannabinoid compounds and methods for enhancing their physiological concentration CNR1, CNR2, FAAH ALDH1A1 1641/4885CYP2C19 189/4885NPC1 726/4885
US-20030096829-A1 1-biaryl-1,8-naphthyridin-4-one phosphodiesterase-4 inhibitors PDE4A, PDE4B, PDE7A ALDH1A1 314/4885CYP2C19 242/4885NPC1 2014/4885
US-20090239848-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE SCD, SCD5, FADS2 ALDH1A1 969/4885CYP2C19 3176/4885NPC1 206/4885
US-20080269192-A1 Chiral Fused [1,2]Imidazo[4,5-C] Ring Compounds IFNAR1, IFNG, IL4 ALDH1A1 1323/4885CYP2C19 2423/4885NPC1 1586/4885
US-20170088559-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES IL2, IFNG, TSLP ALDH1A1 624/4885CYP2C19 1984/4885NPC1 2273/4885
US-20090105295-A1 HYDROXYLAMINE SUBSTITUTED IMIDAZOQUINOLINES IL2, IL4, IFNG ALDH1A1 910/4885CYP2C19 1886/4885NPC1 3976/4885
US-20080318998-A1 Alkyloxy Substituted Thiazoloquinolines and Thiazolonaphthyridines IL2, IFNG, TSLP ALDH1A1 624/4885CYP2C19 1984/4885NPC1 2273/4885
US-11667638-B2 4-substitued cytisine analogues CES2, CDA, PCYT1A ALDH1A1 1941/4885CYP2C19 273/4885NPC1 1347/4885
US-20100324323-A1 Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis ADH1C, ADH1A, CYP2E1 ALDH1A1 66/4885CYP2C19 301/4885NPC1 1965/4885
US-20100069427-A9 Oxime and Hydroxylamine Substituted Imidazo[4,5-c] Ring Compounds and Methods IFNG, IL4, IRF3 ALDH1A1 872/4885CYP2C19 419/4885NPC1 4059/4885
US-20090062328-A1 Oxime and Hydroxylamine Substituted Imidazo[4,5-c] Ring Compounds and Methods IFNG, IL4, IRF3 ALDH1A1 872/4885CYP2C19 419/4885NPC1 4059/4885
US-11267800-B2 Cyclohexyl acid triazole azines as LPA antagonists LPAR3, LPAR1, LPAR2 ALDH1A1 2244/4885CYP2C19 2798/4885NPC1 396/4885
US-20120232057-A1 CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS IFNAR1, IFNG, IL4 ALDH1A1 1278/4885CYP2C19 2384/4885NPC1 1558/4885
US-20220017562-A1 3beta-(benzyloxy)-17alpha-methyl-pregn-5-en-20-one for use in the treatment of cognitive disorders CYP17A1, HSD17B11, CYP11B1 ALDH1A1 1391/4885CYP2C19 102/4885NPC1 349/4885
US-20230270750-A1 CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS BCHE, ACHE, CHAT ALDH1A1 239/4885CYP2C19 303/4885NPC1 3593/4885
US-20050043354-A1 NK1 antagonist TACR2, TACR1, TAC3 ALDH1A1 2855/4885CYP2C19 1890/4885NPC1 659/4885
US-20180201560-A1 BIO-STABLE CANNABINOID COMPOUNDS AND METHODS FOR ENHANCING THEIR PHYSIOLOGICAL CONCENTRATION CNR1, CNR2, FAAH ALDH1A1 1641/4885CYP2C19 189/4885NPC1 726/4885
US-11753376-B2 Benzyloxy pyridine derivatives and uses thereof SQSTM1, ATG7, BECN1 ALDH1A1 3915/4885CYP2C19 3729/4885NPC1 601/4885
US-20070208052-A1 Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines IL2, TSLP, IFNG ALDH1A1 626/4885CYP2C19 2273/4885NPC1 1748/4885
US-20090042925-A1 OXIME SUBSTITUTED IMIDAZOQUINOLINES IFNG, IL2, IRF3 ALDH1A1 1493/4885CYP2C19 1040/4885NPC1 4695/4885
US-20130267564-A1 BENZYLOXYPYRIMIDINE DERIVATIVE, AGRICULTURAL/ HORTICULTURAL INSECTICIDE COMPRISING DERIVATIVE AND METHOD FOR USING SAME HDHD5, DPYSL2, HACL2 ALDH1A1 915/4885CYP2C19 175/4885NPC1 3872/4885
US-20100324324-A1 Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis ADH1C, ADH1A, CYP2E1 ALDH1A1 66/4885CYP2C19 301/4885NPC1 1965/4885
US-20100272677-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS POLR2A, EIF2AK2, RRM2B ALDH1A1 756/4885CYP2C19 522/4885NPC1 1154/4885
US-20180057509-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES IL2, IFNG, TSLP ALDH1A1 624/4885CYP2C19 1984/4885NPC1 2273/4885
US-20110293654-A1 SUBSTITUTED CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS IFNG, IL4, IFNAR1 ALDH1A1 1204/4885CYP2C19 1530/4885NPC1 2676/4885
US-20080085890-A1 Substituted isoquinoline-1,3(2H,4H)-diones, 1-thioxo-1,4-dihydro-2H-isoquinoline-3-ones and 1,4-dihydro-3 (2H)-isoquinolones and methods of use thereof SULT1E1, RECQL, HAX1 ALDH1A1 61/4885CYP2C19 1236/4885NPC1 538/4885
US-20070099901-A1 Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines IFNG, IRF3, IDO1 ALDH1A1 679/4885CYP2C19 657/4885NPC1 4507/4885
US-20110207725-A1 CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS IFNAR1, IFNG, IL4 ALDH1A1 1323/4885CYP2C19 2423/4885NPC1 1586/4885
US-20230203038-A1 4-SUBSTITUED CYTISINE ANALOGUES CES2, CDA, PCYT1A ALDH1A1 1941/4885CYP2C19 273/4885NPC1 1347/4885
US-20080114019-A1 Hydroxylamine Substituted Imidazoquinolines IFNG, IRF3, IL2 ALDH1A1 513/4885CYP2C19 1655/4885NPC1 4215/4885
US-20190345087-A1 BIO-STABLE CANNABINOID COMPOUNDS AND METHODS FOR ENHANCING THEIR PHYSIOLOGICAL CONCENTRATION CNR1, CNR2, FAAH ALDH1A1 2169/4885CYP2C19 178/4885NPC1 794/4885
US-20070066639-A1 Oxime substituted imidazoquinolines IFNG, IRF3, IL2 ALDH1A1 1370/4885CYP2C19 1367/4885NPC1 4636/4885
US-20220402873-A1 NOVEL P62 LIGAND COMPOUND, AND COMPOSITION CONTAINING SAME FOR PREVENTING, AMELIORATING, OR TREATING PROTEINOPATHIES SQSTM1, ATG7, ATG13 ALDH1A1 4802/4885CYP2C19 4311/4885NPC1 291/4885
US-20090005371-A1 Substituted Fused [1,2]Imidazo[4,5-C] Ring Compounds and Methods IL2, IFNG, IL4 ALDH1A1 890/4885CYP2C19 1910/4885NPC1 1960/4885
US-20100226879-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS POLR2A, IFNAR1, RRM2B ALDH1A1 859/4885CYP2C19 1146/4885NPC1 2182/4885
US-20090005376-A1 imidazonaphthyridines, imidazopyridines, imidazoquinolines, and imidazote-trahydroquinolines; immunomodulators for inducing cytokine biosynthesis; for treatment of viral and neoplastic diseases IL2, IL4, IRF3 ALDH1A1 1123/4885CYP2C19 3888/4885NPC1 3978/4885
US-20200172544-A1 COMPOUNDS CES2, CYCS, CHKB ALDH1A1 1652/4885CYP2C19 299/4885NPC1 408/4885
US-20240287073-A1 4-SUBSTITUED CYTISINE ANALOGUES CES2, CDA, PCYT1A ALDH1A1 1941/4885CYP2C19 273/4885NPC1 1347/4885
US-20150307496-A1 NOVEL TRICYCLIC 3,4-DIHYDRO-2H-PYRIDO[1,2-a]PYRAZINE-1,6-DIONE DERIVATIVES AS GAMMA SECRETASE MODULATORS BACE1, BACE2, PSEN1 ALDH1A1 1881/4885CYP2C19 1200/4885NPC1 1025/4885
US-20080085895-A1 Substituted Chiral Fused [1,2]Imidazo[4,5-C] Ring Compounds IFNG, IL4, IFNAR1 ALDH1A1 1204/4885CYP2C19 1530/4885NPC1 2676/4885
US-20040082784-A1 Pyridino and pyrimidino pyrazinones CRHR1, CRHR2, CRH ALDH1A1 882/4885CYP2C19 389/4885NPC1 4017/4885
US-20220298113-A1 BENZYLOXY PYRIDINE DERIVATIVES AND USES THEREOF SQSTM1, ATG7, BECN1 ALDH1A1 3915/4885CYP2C19 3729/4885NPC1 601/4885
US-20100240693-A1 Oxime and Hydroxylamine Substituted Thiazolo [4,5-C] Ring Compounds and Methods IL4, IL2, TH ALDH1A1 502/4885CYP2C19 491/4885NPC1 4507/4885
US-20060019981-A1 Method of preparing inhibitors phosphodiesterase-4 PDE4A, PDE5A, PDE3A ALDH1A1 572/4885CYP2C19 59/4885NPC1 3527/4885
US-11905287-B2 4-substitued cytisine analogues CES2, CDA, PCYT1A ALDH1A1 1941/4885CYP2C19 273/4885NPC1 1347/4885
US-10174021-B2 Substituted pyrazolo[1,5-A]pyridines and their use PNPO, PDXK, XDH ALDH1A1 220/4885CYP2C19 113/4885NPC1 1496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.