SCHEMBL18430366

SCHEMBL18430366

N#Cc1csc2c1CCCCC2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.43
MAPT P10636 4/20 0.43
MAPK1 P28482 3/20 0.43
BPTF Q12830 2/20 0.43
GAA P10253 2/20 0.43
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 2/20 0.43
HPGD P15428 7/20 0.41
SMN1; SMN2 Q16637 5/20 0.37
LMNA P02545 2/20 0.37
GFER P55789 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TP53 P04637 4/20 0.36
HTT P42858 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NPC1 O15118 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15920403 0.98 BPTF (0.41) ALDH1A1MAPTMAPK1BPTFGAA
SCHEMBL21598835 0.76 HTR2A (0.42)
SCHEMBL21598840 0.76 PNMT (0.39)
SCHEMBL23840301 0.71 HPGD (0.44) ALDH1A1MAPTMAPK1GAAHPGD
SCHEMBL15848407 0.71 PNMT (0.41)
SCHEMBL25364670 0.71
SCHEMBL13021599 0.69 HPGD (0.44) ALDH1A1MAPTGAAHPGDSMN1; SMN2
SCHEMBL2039293 0.69 HPGD (0.42) ALDH1A1MAPTHSD17B10HPGDSMN1; SMN2
SCHEMBL25365128 0.68 ADRA1A (0.34) ALDH1A1MAPTHSD17B10SMN1; SMN2NPSR1
Hydrochloric Acid SCHEMBL31564391 0.67 NR2E1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10655091-B2 Thiophene azo dyes and laundry care compositions containing the same THE PROCTER & GAMBLE COMPANY (US) 2020-05-19 US disclosed
US-20190345415-A1 THIOPHENE AZO DYES AND LAUNDRY CARE COMPOSITIONS CONTAINING THE SAME PROCTER & GAMBLE (US) 2019-11-14 US disclosed
US-10435651-B2 Thiophene azo dyes and laundry care compositions containing the same THE PROCTER & GAMBLE COMPANY (US) 2019-10-08 US disclosed
US-20180066215-A1 THIOPHENE AZO DYES AND LAUNDRY CARE COMPOSITIONS CONTAINING THE SAME PROCTER & GAMBLE (US) 2018-03-08 US disclosed
US-9752104-B2 Thiophene AZO carboxylate dyes and laundry care compositions containing the same THE PROCTER & GAMBLE COMPANY (US) 2017-09-05 US disclosed
EP-2638142-B1 THIOPHENE AZO DYES AND LAUNDRY CARE COMPOSITIONS CONTAINING THE SAME PROCTER & GAMBLE (US) 2017-05-10 EP disclosed
US-9567465-B2 Thiophene azo carboxylate dyes and laundry care compositions containing the same MILLIKEN & COMPANY (US) 2017-02-14 US disclosed
US-9556337-B2 Thiophene azo dyes and laundry care compositions containing the same MILLIKEN & COMPANY (US) 2017-01-31 US disclosed