Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15848407 | 0.87 | PNMT (0.41) | HTR2AHTR2CHTR2BPNMTDRD2 | |
| SCHEMBL15920403 | 0.78 | BPTF (0.41) | — | |
| SCHEMBL21598840 | 0.77 | PNMT (0.39) | PNMTDRD2DRD3APEX1 | |
| SCHEMBL18430366 | 0.76 | ALDH1A1 (0.43) | — | |
| SCHEMBL2991516 | 0.72 | HTR2C (0.41) | HTR2AHTR2CHTR2BPNMT | |
| SCHEMBL2996134 | 0.72 | PNMT (0.36) | HTR2AHTR2CHTR2BPNMTAPEX1 | |
| SCHEMBL25364670 | 0.68 | — | — | |
| SCHEMBL25365128 | 0.66 | ADRA1A (0.34) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL31564391 | 0.65 | NR2E1 (0.33) | — | |
| SCHEMBL17377146 | 0.64 | PNMT (0.45) | PNMTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810613-A1 | N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019244047-A1 | N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2019-12-26 | — | — | WO | disclosed |