Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.62 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.62 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.49 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34467320 | 0.88 | NNMT (0.58) | MKNK1MKNK2GPR183OXTRNNMT | |
| SCHEMBL29365356 | 0.82 | MKNK1 (0.73) | MKNK1MKNK2OXTRNNMTHSD17B1 | |
| SCHEMBL1870306 | 0.82 | MKNK1 (0.73) | MKNK1MKNK2OXTRNNMTHSD17B1 | |
| SCHEMBL12641872 | 0.82 | MKNK1 (0.73) | MKNK1MKNK2OXTRNNMTHSD17B1 | |
| SCHEMBL30280631 | 0.82 | MKNK1 (0.73) | MKNK1MKNK2OXTRNNMTHSD17B1 | |
| SCHEMBL2945799 | 0.77 | MKNK1 (0.71) | MKNK1MKNK2OXTRNNMTHSD17B1 | |
| SCHEMBL3728756 | 0.75 | MKNK1 (0.56) | MKNK1MKNK2GPR183HSD17B1HSD17B2 | |
| SCHEMBL3728757 | 0.75 | MKNK1 (0.56) | MKNK1MKNK2GPR183HSD17B1HSD17B2 | |
| SCHEMBL34467450 | 0.75 | NNMT (0.57) | MKNK1MKNK2GPR183OXTRNNMT | |
| SCHEMBL12582087 | 0.75 | MKNK1 (0.68) | MKNK1MKNK2OXTRNNMTHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322507-A1 | Matrix metalloproteinase inhibitors | Ranbaxy Laboratories Limited (IN) | 2011-05-18 | — | — | EP | disclosed |