Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15022265 | 0.77 | MAPK9 (0.60) | MAPK9MAPK10L3MBTL1SMN1; SMN2TUBB4A | |
| SCHEMBL11086703 | 0.77 | MAPK9 (0.68) | MAPK9MAPK10L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL28179567 | 0.76 | HSD11B1 (0.65) | MAPK9MAPK10HSD11B1OPRD1UCHL3 | |
| SCHEMBL15022063 | 0.74 | MAPK10 (0.56) | MAPK9MAPK10L3MBTL1TUBB4ATUBB | |
| SCHEMBL31754153 | 0.72 | OPRD1 (0.55) | MAPK9MAPK10L3MBTL1HSD11B1MAPT | |
| SCHEMBL15022258 | 0.72 | MAPK9 (0.51) | MAPK9MAPK10L3MBTL1TUBB4ATUBB | |
| SCHEMBL11927943 | 0.72 | CYP3A4 (0.52) | L3MBTL1SMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL25215742 | 0.71 | MAPK9 (0.52) | MAPK9MAPK10KMT2AMEN1OPRD1 | |
| SCHEMBL3271173 | 0.71 | OPRD1 (0.52) | MAPK9MAPK10L3MBTL1SMN1; SMN2TUBB4A | |
| SCHEMBL2889930 | 0.68 | L3MBTL1 (0.53) | MAPK9MAPK10L3MBTL1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694652-B1 | MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2017-02-01 | — | — | EP | disclosed |