Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13195961 | 0.74 | MAPK10 (0.47) | MAPK10MAPK9KDRKCNH2AOC3 | |
| SCHEMBL25215742 | 0.73 | MAPK9 (0.52) | MAPK10MAPK9OPRD1MAPK14MEN1 | |
| SCHEMBL15022265 | 0.73 | MAPK9 (0.60) | MAPK10MAPK9OPRD1OPRM1TUBB4A | |
| SCHEMBL11086703 | 0.72 | MAPK9 (0.68) | MAPK10MAPK9OPRD1OPRM1MEN1 | |
| SCHEMBL15022063 | 0.70 | MAPK10 (0.56) | MAPK10MAPK9OPRD1OPRM1TUBB4A | |
| SCHEMBL15709009 | 0.69 | ALDH1A1 (0.64) | MAPK10MAPK9LMNAKMT2AALDH1A1 | |
| SCHEMBL31278174 | 0.69 | CYP3A4 (0.43) | KCNH2CYP11B2CYP17A1CYP1A2MEN1 | |
| SCHEMBL23559029 | 0.69 | CYP3A4 (0.43) | KCNH2CYP11B2CYP17A1CYP1A2MEN1 | |
| SCHEMBL6279167 | 0.68 | KDR (0.39) | KDRBCHEMEN1LMNAMAPT | |
| SCHEMBL18433027 | 0.68 | MAPK9 (0.53) | MAPK10MAPK9OPRD1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694652-B1 | MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2017-02-01 | — | — | EP | disclosed |