Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 17/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434486 | 0.86 | SLC40A1 (0.61) | SLC40A1 | |
| SCHEMBL18434785 | 0.85 | SLC40A1 (0.58) | SLC40A1KDM4E | |
| SCHEMBL18434664 | 0.83 | SLC40A1 (0.55) | SLC40A1MEN1KMT2AKDM4E | |
| SCHEMBL12475058 | 0.81 | SLC40A1 (0.55) | SLC40A1MEN1KMT2AKDM4E | |
| SCHEMBL18434412 | 0.81 | SLC40A1 (0.55) | SLC40A1MEN1KMT2AKDM4E | |
| SCHEMBL18434472 | 0.81 | KDM4E (0.39) | SLC40A1MEN1KMT2APAX8KDM4E | |
| SCHEMBL11973692 | 0.78 | SLC40A1 (0.48) | SLC40A1 | |
| SCHEMBL18434849 | 0.77 | SLC40A1 (0.60) | SLC40A1MEN1KMT2AKDM4E | |
| SCHEMBL11973826 | 0.77 | KDM4E (0.46) | SLC40A1KDM4E | |
| SCHEMBL18434448 | 0.76 | SLC40A1 (0.61) | SLC40A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |