Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 15/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434472 | 0.84 | KDM4E (0.39) | SLC40A1KDM4EL3MBTL1MPIMEN1 | |
| SCHEMBL18434412 | 0.84 | SLC40A1 (0.55) | SLC40A1KDM4EL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL12475058 | 0.84 | SLC40A1 (0.55) | SLC40A1KDM4EL3MBTL1MPIMEN1 | |
| SCHEMBL18434406 | 0.83 | SLC40A1 (0.58) | SLC40A1KDM4EMEN1KMT2A | |
| SCHEMBL18434326 | 0.83 | SLC40A1 (0.60) | SLC40A1KDM4EL3MBTL1MPI | |
| SCHEMBL18434582 | 0.82 | SLC40A1 (0.43) | SLC40A1KDM4EL3MBTL1MPIMEN1 | |
| SCHEMBL11973692 | 0.81 | SLC40A1 (0.48) | SLC40A1 | |
| SCHEMBL11973826 | 0.80 | KDM4E (0.46) | SLC40A1KDM4EL3MBTL1 | |
| SCHEMBL18434707 | 0.79 | SLC40A1 (0.59) | SLC40A1KDM4EL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL18434680 | 0.78 | SLC40A1 (0.58) | SLC40A1KDM4EL3MBTL1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |