Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 14/20 | 0.55 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MMP14 | P50281 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434845 | 0.85 | SLC40A1 (0.58) | SLC40A1CCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL12475058 | 0.84 | SLC40A1 (0.55) | SLC40A1L3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL18434664 | 0.84 | SLC40A1 (0.55) | SLC40A1L3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL18434472 | 0.84 | KDM4E (0.39) | SLC40A1L3MBTL1ALDH1A1MMP14KDM4E | |
| SCHEMBL18434792 | 0.83 | SLC40A1 (0.55) | SLC40A1CCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL18434680 | 0.83 | SLC40A1 (0.58) | SLC40A1CCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL18434806 | 0.82 | SLC40A1 (0.58) | SLC40A1CCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL18434673 | 0.82 | SLC40A1 (0.44) | SLC40A1CCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL18434496 | 0.82 | SLC40A1 (0.61) | SLC40A1CCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL18434406 | 0.81 | SLC40A1 (0.58) | SLC40A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |