Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 11/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434840 | 0.89 | SLC40A1 (0.53) | SLC40A1HPGDKDM4EMEN1MAPK1 | |
| SCHEMBL18434695 | 0.81 | SLC40A1 (0.63) | SLC40A1KDM4E | |
| SCHEMBL18434466 | 0.81 | SLC40A1 (0.69) | SLC40A1HPGDKDM4EMEN1MAPK1 | |
| SCHEMBL11995689 | 0.80 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434817 | 0.77 | SLC40A1 (0.57) | SLC40A1KDM4E | |
| SCHEMBL18434471 | 0.75 | SLC40A1 (0.66) | SLC40A1HPGDKDM4ETGFBR1TP53 | |
| SCHEMBL18434678 | 0.72 | SLC40A1 (0.57) | SLC40A1HPGDKDM4EMEN1MAPK1 | |
| SCHEMBL11997062 | 0.70 | SLC40A1 (0.82) | SLC40A1 | |
| SCHEMBL16285219 | 0.70 | SLC40A1 (0.62) | SLC40A1KDM4EMEN1KMT2A | |
| SCHEMBL11995690 | 0.69 | SLC40A1 (0.80) | SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |