Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 10/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18434655 | 0.83 | SLC40A1 (0.66) | SLC40A1KDM4ESMN1; SMN2 | |
| SCHEMBL18434677 | 0.82 | SLC40A1 (0.68) | SLC40A1KDM4EMEN1KMT2ATP53 | |
| SCHEMBL11995689 | 0.81 | SLC40A1 (1.00) | SLC40A1 | |
| SCHEMBL18434463 | 0.81 | SLC40A1 (0.67) | SLC40A1HPGDKDM4EMEN1MAPK1 | |
| SCHEMBL18434694 | 0.80 | SLC40A1 (0.65) | SLC40A1KDM4E | |
| SCHEMBL18434461 | 0.76 | SLC40A1 (0.69) | SLC40A1 | |
| SCHEMBL18434773 | 0.76 | SLC40A1 (0.59) | SLC40A1KDM4E | |
| SCHEMBL18434807 | 0.75 | SLC40A1 (0.70) | SLC40A1 | |
| SCHEMBL18434683 | 0.75 | SLC40A1 (0.62) | SLC40A1KDM4EMEN1KMT2ATP53 | |
| SCHEMBL18434473 | 0.74 | SLC40A1 (0.68) | SLC40A1HPGDKDM4ETP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |